SpeciesT_s * ISM-GasISM-DustMost CometsP/HalleyHyakutakeHale-BoppImplications H2OH2O CH 3 OH Consistent with grains in ISM cloud cores HCN NH Consistent with molecular clouds CO H 2 CO Variable in P/Halley CH First good detection in Hyakutake CO Distributed source and nuclear source in Halley N2N S2S Seen in only 1 comet before C2H6C2H Could be a lower limit CH 4 :CO Comet and ISM Composition Comparison