Molecular and cellular biology D. Gurarie
Biochemistry Basic components: proteins, hydrocarbons, lipids, nucleic acids, other Basic processes: Metabolism: building (assembling, disassembling) intra/extra cellular components, removal of waste products. Energy transfer. Energy is typically stored in large molecules like ATP, or polymers (polysaccharides, lipids, proteins) Catabolism: break-up of polymers into monomers (monosaccharides, fatty acids, amino acids), the excess energy being stored (ADP-> ATP) Anabolism synthesis of polymers from monomers (requires energy from ATP) Signaling and cellular function/control (activation, proliferation, death) Neural transmission Many metabolic (and other biochemical) processes are controlled by ultra- efficient catalysts – enzymes (complex proteins)
Example: ADT-ATP kinetics ATP kinetics and structure Anabolism Catabolism