Electroencephalography Electrical potential is usually measured at many sites on the head surface.

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Presentation transcript:

Electroencephalography Electrical potential is usually measured at many sites on the head surface

Electroencephalography Electrical potential is usually measured at many sites on the head surface More is sometimes better

Electroencephalography EEG changes with various states and in response to stimuli

The Event-Related Potential (ERP) Embedded in the EEG signal is the small electrical response due to specific events such as stimulus or task onsets, motor actions, etc.

The Event-Related Potential (ERP) Embedded in the EEG signal is the small electrical response due to specific events such as stimulus or task onsets, motor actions, etc. Averaging all such events together isolates this event-related potential

The Event-Related Potential (ERP) We have an ERP waveform for every electrode

The Event-Related Potential (ERP) We have an ERP waveform for every electrode Sometimes that isn’t very useful

The Event-Related Potential (ERP) We have an ERP waveform for every electrode Sometimes that isn’t very useful Sometimes we want to know the overall pattern of potentials across the head surface –isopotential map

The Event-Related Potential (ERP) We have an ERP waveform for every electrode Sometimes that isn’t very useful Sometimes we want to know the overall pattern of potentials across the head surface –isopotential map Sometimes that isn’t very useful - we want to know the generator source in 3D

Brain Electrical Source Analysis Given this pattern on the scalp, can you guess where the current generator was?

Brain Electrical Source Analysis Given this pattern on the scalp, can you guess where the current generator was?

Brain Electrical Source Analysis Source Analysis models neural activity as one or more equivalent current dipoles inside a head- shaped volume with some set of electrical characteristics

Brain Electrical Source Analysis Initiate the model

Brain Electrical Source Analysis Initiate the model Project “Forward Solution”

Brain Electrical Source Analysis Initiate the model Project “Forward Solution” Compare to actual data

Brain Electrical Source Analysis Adjust the model Project “Forward Solution” Compare to actual data

Brain Electrical Source Analysis This is most likely location of dipole Project “Forward Solution” Compare to actual data