The TrueBeam System ™ Clinic Name Presenter’s name Clinic location Date Use this PowerPoint to educate staff and referring physicians about the features, benefits and advantages of your new TrueBeam system. It has been created to be “presentation-ready” with both slides and talking points. Of course, feel free to customize or use this as a guide in creating your own PowerPoint presentation.

Welcome Welcome and thank attendees for coming. Briefly discuss the acquisition of TrueBeam technology, an advanced radiotherapy system from Varian Medical Systems that unlocks new treatment opportunities for patients with cancer. Introduce video. 2

TrueBeam Unlocks Treatments Fast and Precise Enhanced Patient Comfort ™ TrueBeam Unlocks Treatments Fast and Precise Enhanced Patient Comfort

™ TrueBeam Unlocks Treatments

New Architecture TrueBeam Unlocks Treatments ™ TrueBeam Unlocks Treatments New Architecture The TrueBeam system has been designed from the ground up to optimize radiotherapy and radiosurgery Delivers powerful cancer treatments with pinpoint accuracy and precision Seamless integration of treatment, imaging and motion management

New Beam Generation System ™ TrueBeam Unlocks Treatments All new accelerator guide Variable energy switch Simplified and integrated bend magnet New energy/foil carousel and target system Real-time electron gun gating Maximum flexibility in dosimetry <5 MU/min up to 2400 MU/min New Beam Generation System

More Treatment Options ™ TrueBeam Unlocks Treatments Provide more options for treating complex cancer cases including lung, breast, liver, abdomen, head and neck IMRT, IGRT, RapidArc, Gated RapidArc, SBRT, SRS More Treatment Options

Gated RapidArc TrueBeam Unlocks Treatments Next evolutionary step ™ TrueBeam Unlocks Treatments Next evolutionary step Compensates for tumor motion Expands application of RapidArc treatments to moving tumors Enables fast treatments of tumors that move with respiration Minimizes exposure to healthy tissues Gated RapidArc

TrueBeam Gated RapidArc ™

™ TrueBeam Fast and Precise

= TrueBeam Fast and Precise Synchronized Fast & Precise Treatments ™ Imaging & Delivery = Fast & Precise Treatments

Enhanced Image Guidance TrueBeam Fast and Precise ™ Simplified, Automated Imaging Modes Image Acquisition during Treatment—kV and MV Respiration synchronized kV and MV Imaging Enhanced Image Guidance

TrueBeam kV Paired Imaging ™

TrueBeam Cone Beam CT - CBCT ™

TrueBeam MV Imaging ™

TrueBeam Fluoroscopy ™

25 % Less Dose TrueBeam Fast and Precise ™ 25 IGRT with CBCT in 60% less time* Added imaging functionality can allow 25% less dose* % Less Dose *Comparisons, Data on file, Trilogy system, Varian Medical Systems, 2010

TrueBeam Diagnostic CT vs. CBCT ™ Diagnostic CT CBCT

Pinpoint Accuracy TrueBeam Fast and Precise ™ Mechanical and Imaging Isocenter Accuracy < 0.75 mm Gantry rotational: < 0.3 degrees Collimator rotational: < 0.5 degrees Pinpoint Accuracy

7 Minutes TrueBeam Fast and Precise Gated RapidArc Lung Treatment ™ 7 Gated RapidArc Lung Treatment 18 Gy, 2 arcs, 10X High Intensity Mode Minutes

2.5 < Minutes TrueBeam Fast and Precise ™ 2.5 5 field IMRT prostate, 1.8 Gy 5 large field IMRT head and neck, 1.8 Gy < Minutes

Higher Dose Rate TrueBeam Fast and Precise ™ Enables fast hypofractionation Fast High Intensity Mode —6X: max ~1400 MU/min Yields higher dose rates* Higher Dose Rate *Compared to current Varian technology

50 % Faster TrueBeam Fast and Precise ™ 50 One button image acquisition and full automation of beam delivery make treatments 50% faster* With faster treatments, there is less patient movement % Faster *Comparisons, Data on file, Trilogy system, Varian Medical Systems, 2010

Unrivaled Treatment Precision TrueBeam Fast and Precise ™ Unrivaled Treatment Precision Accuracy in increments of less than a millimeter Submillimeter alignment for imaging and treatment isocenter Performs accuracy checks every 10 milliseconds throughout treatment

Multiple Energy Support TrueBeam Fast and Precise ™ 6 X-ray energies 8 electron energies Tailor treatments to individual patients Optimal energy selction for specific clinical need Multiple Energy Support

Enhanced Patient Comfort ™ TrueBeam Enhanced Patient Comfort

Built with Patient Comfort in Mind TrueBeam Enhanced Patient Comfort ™ Quiet operation provides for more comfortable environment Shorter treatment times, less interruption to patient’s daily lives Music can be played during treatments to increase patient comfort Built with Patient Comfort in Mind

Enhanced Patient Interaction TrueBeam Enhanced Patient Comfort ™ Constant interaction between the patient and therapist New communication system enables the therapist to monitor the patient from outside the treatment room Enhanced Patient Interaction

Allow more time with patient TrueBeam Enhanced Patient Comfort ™ Guided workflow Streamlined tasks Prompted and predicted next steps Common user interface for Console, Pendant and Couch controls Allow more time with patient

TrueBeam Treatment Console ™

TrueBeam ™ Radically Different

Radically Different TrueBeam Summary ™ Designed to optimize radiotherapy and radiosurgery Integrates and choreographs powerful imaging and treatment systems Unparalleled accuracy and speed Unlocks new treatment options Enhanced patient comfort Radically Different

Thank You Varian Medical Systems