Neutralizing Power of Antacids Due Today: 1. Neutralizing Power of Antacids Pre-Lab 2. Acid-Base Short Lab Report Homework: 1. Neutralizing Power of Antacids Formal Lab Report 2. Iron Content Analysis Pre-Lab Neutralizing Power of Antacids

Objective Measure neutralizing capacity of a commercial antacid Determine which brand is most cost effective

Procedure Notes Part I: Standardizing NaOH Completed in Acid-Base Titration Lab

Procedure Notes Part II: Titration with simulated Stomach Acid Use graduated pipettes Add bromophenol blue indicator Yellow → Blue Make sure there is no green tint!

Procedure Notes Part III: Stomach acid/Antacid Reaction Record all pertinent information from packaging Use graduated pipets GENTLY heat Heat no higher than 3 Some solids may remain Keep track of the # of pipets added

Procedure Notes Part IV: Neutralizing excess Stomach Acid Use GRADUATED pipets Add bromophenol blue indicator Yellow → Blue Make sure there is no green tint!

Waste Titrated solutions → dispose in the sink Excess NaOH → place in large carboy

Risk assessment Hydrochloric Acid Sodium Hydroxide Danger Inhalation Hazard Corrosive Sodium Hydroxide

moles=M x V calculations Total Moles of HCl added to antacid: V= (total number of pipets used) 1 Pipet = 25.00 mL

m𝑜𝑙𝑒𝑠 𝑛𝑒𝑢𝑡𝑟𝑎𝑙𝑖𝑧𝑒𝑑 1 𝑡𝑒𝑎𝑠𝑝𝑜𝑜𝑛 𝑥 # 𝑜𝑓 𝑡𝑒𝑎𝑠𝑝𝑜𝑜𝑛𝑠 𝑑𝑜𝑠𝑒 calculations Moles neutralized per dose m𝑜𝑙𝑒𝑠 𝑛𝑒𝑢𝑡𝑟𝑎𝑙𝑖𝑧𝑒𝑑 1 𝑡𝑒𝑎𝑠𝑝𝑜𝑜𝑛 𝑥 # 𝑜𝑓 𝑡𝑒𝑎𝑠𝑝𝑜𝑜𝑛𝑠 𝑑𝑜𝑠𝑒 Dose of antacid per dollar 𝑑𝑜𝑠𝑒 𝑐𝑜𝑠𝑡 =𝑑𝑜𝑠𝑒/$

𝑚𝑜𝑙𝑒𝑠 𝑑𝑜𝑠𝑒 𝑥 𝑑𝑜𝑠𝑒 $ =𝑚𝑜𝑙𝑒𝑠/$ Calculations Moles HCl neutralized per dollar 𝑚𝑜𝑙𝑒𝑠 𝑑𝑜𝑠𝑒 𝑥 𝑑𝑜𝑠𝑒 $ =𝑚𝑜𝑙𝑒𝑠/$ You must collect ALL groups moles/$ values

Antacid information Antacid Active Ingredients Price Quantity Dose Rolaids $4.99 150 tablets 3 tablets Tums $5.79 Mylanta $6.29 12 fluid ounces 3 teaspoons Maalox $5.89 Milk of Magnesia $6.49 2 teaspoons

Cost effectiveness comparison Antacid average experimental neutralizing capacity per dollar theoretical moles HCl neutralized per dose theoretical neutralizing Capacity per Dollar percent difference Rolaids   Tums Mylanta Maalox Milk of Magnesia