excel HR ™ 21 st Century Hair Removal

Nd:YAG 1064 nm Skin Types I-VI Safest wavelength for darker skin and tanned patients Effective on dark, coarse hair Nd:YAG 1064 nm Skin Types I-VI Safest wavelength for darker skin and tanned patients Effective on dark, coarse hair Pulsed Light (IPLs) 590 to 1200 nm Skin Types I-V; best for light skin and dark hair Shallower penetration – deeper, thicker hairs not treated as effectively Less precise – can lead to heating of skin pigment Pulsed Light (IPLs) 590 to 1200 nm Skin Types I-V; best for light skin and dark hair Shallower penetration – deeper, thicker hairs not treated as effectively Less precise – can lead to heating of skin pigment Alexandrite 755 nm Skin Types I-V; ‘gold standard’ for I-IV More effective for finer, lighter hair Most globally requested, trusted and utilized wavelength Alexandrite 755 nm Skin Types I-V; ‘gold standard’ for I-IV More effective for finer, lighter hair Most globally requested, trusted and utilized wavelength Diode Laser 800, 810 nm Skin Types I-III; less for IV, V Peak Power/Brightness is a fraction of Nd:YAG/Alex lasers – can be less effective on finer, lighter hair Blind to treatment area Diode Laser 800, 810 nm Skin Types I-III; less for IV, V Peak Power/Brightness is a fraction of Nd:YAG/Alex lasers – can be less effective on finer, lighter hair Blind to treatment area Hair Removal Light Source Comparison

CUTERA’s excel HR redefines effective, safe and comfortable laser hair removal for the 21 st century Technology High-powered proven Alex, Only true long pulse Nd:YAG Technology High-powered proven Alex, Only true long pulse Nd:YAG Versatility All Skin Types, Superior for Leg Veins Versatility All Skin Types, Superior for Leg Veins Performance High-Powered 755 nm / 1064 nm laser Performance High-Powered 755 nm / 1064 nm laser Introducing excel HR! Advanced 21 st Century Hair Removal Comfort Superior Sapphire Contact Cooling Comfort Superior Sapphire Contact Cooling Thoughtfully engineered to meet the needs of customers that have high-volume hair removal practices, and want to treat all skin types

Versatile, High Performance  High-Power 755 nm Alexandrite + Versatile 1064 nm Nd:YAG  Effectively treats ALL skin types  Easily set 3 –18 mm spot sizes optimized for hair and vascular Rapid, powerful energy delivery  Coverage rate 5.1 cm 2 /sec (755 nm)  truPulse ™ consistent long pulse energy delivery (1064 nm) Comfortable treatments with Sapphire contact cooling  The only high power Alex product on the market with contact cooling  Effective, safe, comfortable  Superb visibility of treatment site 4 excel HR Advanced 21 st Century Hair Removal

Compact & Modern Design Small footprint Quick start up Runs quiet and cool Plugs into 220v No Disposables or Consumables No consumables, no CFC’s, no per shot, per patient costs Intuitive User Interface Easy to navigate parameters Real Time Calibration System continually monitors laser output to ensure each laser pulse is exactly the same. No waiting for calibration High-power Alexandrite and Long- pulse Nd:YAG Laser 50J Alex/80J Nd:YAG Max Energy Proprietary truPulse™ technology – the only true long pulse Nd:YAG Up to 2 Hz Alex/10 Hz Nd:YAG Superior Sapphire Contact Cooling Pre, parallel and post-cooling excel HR Advanced Design, Modern Ergonomics Modern Ergonomics Robust, extra-long 3 meter fiber for optimal reach and easy patient access Motorized spot size adjust – no switching of fiber-optic assemblies

Excellent Visibility Large diameter sapphire window Visibility throughout treatment Adjustable Spot Size Motorized, on-the-fly adjustments No switching of fiber-optic assemblies 3-18 mm (Nd:YAG); 5-18 mm (Alex) Real time calibration Sapphire Contact Cooling Clinically superior for laser hair removal Pre-, parallel-, and post-cooling Adjustable temperature sapphire window 4°C to 20 °C excel HR Intelligent Energy Delivery

1064 nm Nd:YAG excel HR Treat All Skin Types I – VI 755 nm Alexandrite

Most trusted and utilized wavelength for laser hair removal globally Only laser with sufficient melanin absorption and peak power to effectively remove finer, lighter hair Has proven long-term results for permanent hair reduction in skin phototypes 1-IV 1,2 and is considered the ‘gold standard’ for treatment of these skin types The Alex wavelength is preferentially absorbed by melanin and an optimized pulse width efficiently targets small to medium follicular structures with less thermal diffusion 1. Grunewald S et al. Lasers Surg Med 2014; 46: Davoudi SM et al. Arch Dermatol 2008; 144(10): excel HR High-Power 755 nm Alexandrite

Cutera recognized as world leader in 1064 nm technology Only truPulse ™ 1064 nm laser on the market  Measurably delivers consistent levels of long pulse energy, pulse after pulse (not a composite pulse) Greater depth of penetration than other lasers Lower melanin absorption (ideal for darker skin types) Long-pulsed Nd:YAG is considered the safest wavelength for hair removal in skin types IV-VI, as well as tanned skin – it safely and effectively targets larger deeper follicular structures in darker skin types excel HR Long-Pulse 1064 nm Nd:YAG 10 msec truPulse ™ Competitor “10 msec”

Sapphire Contact Cooling The Importance of Cooling Melanin is the target in hair follicles, but is also a target in the epidermis  Cooling reduces the temperature rise in the epidermis and protects it from damage, permitting higher fluences to be delivered to the hair follicles Cooling acts as a local anesthetic for improved comfort

Sapphire Contact Cooling The Patient’s Choice Patient preference study*  5 subjects, Single LHR treatment  ½ Tx with excel HR, ½ Tx with GentleMax Pro  Energy delivery levels closely matched  Patients rated pain score, overall satisfaction level 100% of subjects preferred the excel HR treatment overall! All subjects found excel HR to be the more comfortable Tx! excel HR was 20% more comfortable on average! *Data on file

Sapphire Contact Cooling Improved Efficacy with the Sapphire Lens Minimizing the light bending (refraction) ensures that more of the light reaches the target tissue Matching the light path with the refractive index allows the light to back scatter and escape without causing heat build up at the skin’s surface – this is referred to as optical damping Sapphire contact cooling creates near ideal conditions for optical damping – a thin liquid layer can be used to provide optical coupling and enhance the optical damping effect Index matching between sapphire and skin allows back scattered light to escape, further protecting the epidermis from heat build-up Refractive index mismatch causes internally reflected laser light to accumulate under the skin and contribute to epidermal heating

Pre-Tx Clinical Results Preliminary Clinical Treatment (755 nm) – Patient X (Chest) 6 Weeks Post 1 Tx Photos courtesy of Cutera Research Center

Clinical Results Preliminary Clinical Treatment (755 nm) – Patient Y (Full Back) Photos courtesy of Cutera Research Center Skin Type V Pre-Tx6 Weeks Post 1 Tx 3 Months Post 1 Tx

Clinical Results Preliminary Clinical Treatment (755 nm) – Partial Back Photos courtesy of Cutera Research Center Pre-Tx 6 Weeks Post 1 Tx3 Months Post 1 Tx

Pre-Tx Clinical Results Preliminary Clinical Treatment (755 nm) – Patient Z (Under Arm) 6 Weeks Post 1 Tx Photos courtesy of Cutera Research Center 3 Months Post 1 Tx

Pre-Tx Clinical Results 1064 nm Nd:YAG Laser Hair Removal Post-Tx Photos courtesy of Eliot F. Battle, Jr., MD Skin Type V

Pseudofolliculitis Barbae Clinical Results 1064 nm Nd:YAG Laser Hair Removal Pre-Tx Post-Tx Photos courtesy of Cutera Research Center

Clinical Results 1064 nm Nd:YAG Laser Hair Removal Pre-TxPost-Tx Photos courtesy of Samuel Lederman, MD

excel HR Summary excel HR is the modern day solution for hair removal, redefining safe, effective, and comfortable laser hair removal treatments Combination of 755 nm nm can treat ALL skin types Fastest, most powerful hair removal system on the market Integrated Sapphire contact cooling Only true long pulse Nd:YAG Rapid ROI with low cost of ownership & no consumable costs Efficient operation with motorized spot size adjust & real time calibration Handpiece design provides superb visibility of treatment site Versatile – best Nd:YAG on the market for treating veins 20