Psychopharmacology [Instructor name] [Class name section number]

Overview Introduction Pharmacokinetics Drug Administration Drug Metabolism Treatment Approaches – Discussion Special Populations and Psychopharmacology Activity

Introduction Psychoactive Drugs  Communication between neurons Neurotransmitter Activity  Agonists – increase  Antagonists – decrease Side Effects

Overview Introduction Pharmacokinetics Drug Administration Drug Metabolism Treatment Approaches – Discussion Special Populations and Psychopharmacology Activity

Pharmacokinetics Drug effects in the body  Absorption  Distribution  Metabolism  Excretion

Overview Introduction Pharmacokinetics Drug Administration Drug Metabolism Treatment Approaches – Discussion Special Populations and Psychopharmacology Activity

Drug Administration Absorption  Slowest: Oral  Fastest: Intravenous/Inhalation Rapid Absorption = high abuse potential

Overview Introduction Pharmacokinetics Drug Administration Drug Metabolism Treatment Approaches – Discussion Special Populations and Psychopharmacology Activity

Drug Metabolism  Liver enzymes  Repeated exposure  Tolerance  Enzyme induction  Dangers of grapefruit juice

Overview Introduction Pharmacokinetics Drug Administration Drug Metabolism Treatment Approaches – Discussion Special Populations and Psychopharmacology Activity

Treatment Approaches Pharmacology + Therapy = Most Effective Medication can be problematic due to individual variations.

Discussion What is the best treatment for depression?depression

Overview Introduction Pharmacokinetics Drug Administration Drug Metabolism Treatment Approaches – Discussion Special Populations and Psychopharmacology Activity

Juveniles and Psychopharmacology  High prevalence  Difficult to prescribe and research  Increase in diagnoses

The Elderly and Psychopharmacology  Rapidly aging population  Polypharmacy  Risks

Overview Introduction Pharmacokinetics Drug Administration Drug Metabolism Treatment Approaches – Discussion Special Populations and Psychopharmacology Activity

SSRIs, Suicidality, Violence, and Mania  Why doesn’t everyone just take a “happy pill”?  Serious side-effects  What are other barriers to drug therapies?

Medication Adherence Easy as can be… right? Diagnosis: HIV Treatment: Kool-Aid packets/tic-tac mints Must adhere to the assigned treatment protocol What will make treatment easier/harder?

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