KEGG: Kyoto Encyclopedia of Genes and Genomes Susan Seo Intro to Bioinformatics Fall 2004.

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Presentation transcript:

KEGG: Kyoto Encyclopedia of Genes and Genomes Susan Seo Intro to Bioinformatics Fall 2004

KEGG Purpose & Overview Features Example

Purpose Developed at the Kanehisa Laboratory Integrates: –current knowledge of molecular interaction networks –information about genes and proteins –information about chemical compounds and reactions

Overview PATHWAY database GENES / SSDB / KO databases COMPOUND / GLYCAN / REACTION databases

Parkinson’s Disease Search the Pathway database Explore a pathway linked with Parkinson’s disease in humans Look more closely at the PARK2 gene

Features OC Viewer Gene catalog SSDB LinkDB Position Amino Acid sequence Nucleotide Sequence

Conclusion The Kyoto Encyclopedia of Genes and Genomes is a vast library of information gathered from fully sequenced genomes, genes, proteins, pathways, and chemical compounds pertaining to over a hundred different species of both prokaryotes and eukaryotes