LJ-001
Enveloped and Naked Viruses Modes of Infection LJ-001
Gary E. Kaiser
Enveloped and Naked Viruses Modes of Infection LJ-001
Russell Kightley Media
Naked Naked Lytic cycle Exocytosis Enveloped Dan Stowell Botany Online Visual Resource Library
Enveloped and Naked Viruses Modes of Infection LJ-001
A small anti-viral molecule effective against enveloped (but not naked) viruses. Wolf et. al.
Influenza A Filoviruses Poxviruses Arenaviruses Bunyaviruses Paramyxoviruses Flaviviruses HIV-1 Hepatitis C Ebola And others
Viruses can’t make their own proteins or repair their membrane like a cell can
Russell Kightley Media
Wolf et. al.
Still very early in development, further testing needed Shorten Viral Infection Course Preventative Measure? Could be put in condoms New treatment for multiple viruses Eliminate temporary infections Fight Chronic ones LJ001 is effective at very low doses Potentially Excellent Therapeutic Index
Russell Kightley Media Virco Online Humanitarian Futures Programme Gary E. Kaiser HOPES (The Huntinton’s Disease Outreach Project for Education) at Stanford Molecular Station
Wolf et. al. A broad-spectrum antiviral targeting entry of enveloped viruses. Proc Natl Acad Sci U S A Feb 16;107(7): Epub 2010 Jan 28. Balzarini J. Targeting the glycans of glycoproteins: a novel paradigm for antiviral therapy. Nat Rev Microbiol Aug;5(8): Kudchodkar S., Levine, B. Viruses and Autophagy. Reviews in Medical Virology. 2009; 19: Melikyan GB. Common principles and intermediates of viral protein- mediated fusion: the HIV-1 paradigm. Retrovirology Dec 10;5:111.
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