Ch18 Pattern Formation – Regeneration Types of Regeneration: 1.Stem Cells (undifferentiated) 2.Morphallaxis 3.Epimorphosis 4.Compensatory Regeneration (differentiated)
Pattern Formation Regeneration Epimorphosis
Regeneration Epimorphosis Limb regeneration - Blastema What is necessary for limb regeneration? Denerve then amputated ? Amputation add NGF ? Nerve transplants in animals which normally lack regeneration: Newborn Opposum 1. Hindlimb Amputation ? 2.Supplemental nerve tissue ?
Epimorphosis
Hydra freshwater cnidarian Morphallaxis
Hydra – regeneration gradients Head Activator vs. Head Inhibitor both from Hypostome Budding - level of HA at gastric bud Role of nerves
Compensatory Regeneration