Male Reproductive Function Anatomy Hormonal Control Pathophysiology.

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Presentation transcript:

Male Reproductive Function Anatomy Hormonal Control Pathophysiology

Male Reproductive Function Anatomy Hormonal Control Pathophysiology

Testicular Anatomy

Spermatogenesis

Sertoli cell nucleus

Cross-section of seminiferous tubule

Male Reproductive Function Anatomy Hormonal Control Pathophysiology

Hypothalamo-pituitary-gonadal axis GnRH FSH LH Leydig cells testosterone Sertoli cells Androgen binding proteinsinhibin - ? - spermatogonia T response to 5 minute conversation talking to malestalking to females % increase in T

Sertoli cell nucleus Leydig cells LH T FSH ABP inhibin 2  sex characteristics

Male Reproductive Function Anatomy Hormonal Control Pathophysiology

Precocious Puberty Temperature Sensitivity of Sperm Production Hypogonadism –hyperprolactinemia –Feminizing adrenocortical carcinoma –Cannabinoids –HIV Hypergonadism Gynocomastia use of anabolic steroids Environmental effects on sperm count