Organic chemistry for medicine and biology students Chem 2311 Chapter 5 Stereochemistry By Prof. Dr. Adel M. Awadallah Islamic University of Gaza.

Slides:



Advertisements
Similar presentations
chemistry in three dimensions
Advertisements

Stereochemistry chemistry in three dimensions. Isomers – different compounds with the same molecular formula. Structural Isomers – isomers that differ.
5. STEREOISOMERISM. (approx. lecture time: 5 hr) Topics covered: Left and Right hands are not the same (not superimposable) There are also “Left”
Chapter 5- Chirality. Chirality A chiral object is an object that possesses the property of handedness A chiral object, such as each of our hands, is.
Chapter 5: Stereoisomerism
Organic Chemistry 4 th Edition Paula Yurkanis Bruice Irene Lee Case Western Reserve University Cleveland, OH ©2004, Prentice Hall Chapter 5 Stereochemistry.
The study of the three dimensional structure of molecules.
1 Stereochemistry Prof. Dr. Harno Dwi Pranowo Austrian-Indonesian Center for Computational Chemistry Chemistry Department, FMIPA UGM.
constitutional isomers:
Chapter 6 Stereochemistry.
CHE 240 Unit IV Stereochemistry, Substitution and Elimination Reactions CHAPTER FIVE Terrence P. Sherlock Burlington County College 2004.
© Prentice Hall 2001Chapter 41 Naming Enantiomers: The R,S System of Nomenclature 1.Rank groups by atomic number of the atom bonded to the chirality center.
Topics in Stereochemistry. Chiral Carbon Atoms A sp 3 hydbridized carbon atom with four different substituents is chiral. Chiral carbon atoms are also.
Stereoisomerism Nanoplasmonic Research Group Organic Chemistry Chapter 5.
Why Stereochemistry? Stereo isomers Optical Activity – Optical Isomers Optical Rotation Chirality-Chiral atom-Chiral molecules Enantiomers Specifying.
Final material.  What different pathways have we talked about that are new?  Halogenalkane to nitrile or amine.  Nitrile to amine.  Amine and carboxylic.
4 Types of Isomers Structural Isomers/(Constitutional)
3 3-1 Organic Chemistry William H. Brown & Christopher S. Foote.
Stereochemistry Stereoisomerism.
Chapter 4: Stereochemistry. Introduction To Stereochemistry Consider two of the compounds we produced while finding all the isomers of C 7 H 16 : 2-methylhexame.
Stereochemistry & Chiral Molecules. Isomerism Isomers are different compounds with the same molecular formula 1) Constitutional isomers: their atoms are.
1 Stereoisomerism Chapter 26 Hein * Best * Pattison * Arena Colleen Kelley Chemistry Department Pima Community College © John Wiley and Sons, Inc. Version.
4 Types of Isomers. 1.Structural Isomers/(Constitutional) 2.Geometric Isomers/(Cis/Trans) 3.Optical Isomers A.Enantiomers B.Diastereomers.
Chapter 5: Stereoisomerism Stereoisomers are compounds that have the same structural formula in terms of order of attachment, but differ in arrangements.
Chapter 15 The Three-Dimensional Shape of Molecules CHEM 2124 – General Chemistry II Alfred State College Professor Bensley.
CHE 311 Organic Chemistry I Dr. Jerome K. Williams, Ph.D. Saint Leo University.
Chapter 7 Stereochemistry
Stereochemistry 1. Stereoisomerism 2. Chirality
Introduction to Organic Chemistry 2 ed William H. Brown
Properties of Chiral Molecules: Optical Activity.
Stereochemistry Chiral Molecules
Constitutional Isomers
Chapter 5 Stereochemistry: Chiral Molecules 1.
Chemistry 2100 Chapter 15. Enantiomers Enantiomers: Enantiomers: Nonsuperposable mirror images. –As an example of a molecule that exists as a pair of.
Stereochemistry of organic compounds-i. Stereochemistry Stereochemistry, a subdiscipline of chemistry, involves the study of the relative spatial arrangement.
Isomers are compounds which have the same molecular formula, but differ in the way the atoms are arranged. There are three types of isomers constitutional.
Chapter 5 Stereochemistry: Chiral Molecules
Chapter 7 - Stereochemistry Enantiomers of bromochlorofluoromethane Non-superimposable mirror images – Enantiomers.
Stereochemistry. Required background: Shapes of molecular structures Isomers, conformers Essential for: 1. Understanding of S N 1, S N 2, E1, E2, and.
Stereochemistry. Stereochemistry: – The study of the three-dimensional structure of molecules Structural (constitutional) isomers: – same molecular formula.
Chiral Molecules Chapter 5.
Stereochemistry 240 Chem Chapter 5 1. Isomerism Isomers are different compounds that have the same molecular formula.
Stereochemistry at Tetrahedral Centers. Chapter 52 Isomerism: Constitutional Isomers and Stereoisomers – Stereoisomers are isomers with the same molecular.
Isomers Are different compounds with the same molecular formula
Enantiomers rotate plane polarized light the same magnitude, but opposite directions. clockwise rotation – dextrarotatory (d or +) counterclockwise.
Stereochemistry of organic compounds
chemistry in three dimensions
Stereochemistry Chiral Molecules
Cyclohexane and its Stereochemistry
Stereochemistry Stereochemistry refers to the
Chapter 5 Stereochemistry Adel M. Awadallah Islamic University of Gaza
Chapter 5 Stereochemistry Adel M. Awadallah Islamic University of Gaza
Stereoisomerism.
Chapter 20.3: Stereoisomerism
Stereochemistry Stereochemistry refers to the
Optical Isomers.
Chapter 5 Stereochemistry: Chiral Molecules
Chapter 9 Stereochemistry.
Chapter 1 Introduction Adel M. Awadallah Islamic University of Gaza
Islamic University of Gaza
Chapter 5 Stereochemistry: Chiral Molecules
240 Chem Stereochemistry Chapter 5.
Chapter 4: Stereochemistry
240 Chem Stereochemistry Chapter 5.
Stereochemistry Stereochemistry refers to the
Chapter 1 Introduction Bonding and Isomerism
Chapter 5 Stereochemistry Adel M. Awadallah Islamic University of Gaza
Stereochemistry.
Chapter 5 Stereochemistry Adel M. Awadallah Islamic University of Gaza
240 Chem Stereochemistry Chapter 5.
Presentation transcript:

Organic chemistry for medicine and biology students Chem 2311 Chapter 5 Stereochemistry By Prof. Dr. Adel M. Awadallah Islamic University of Gaza

Stereochemistry Isomers: different compounds having the same molecular formula

A chiral molecule is one that is optically active A racemic mixture (racemic modification) is one with equal ratios of enantiomers (50:50 mixture)

Configuration and the R-S Convention

Examples

Compounds with more than one stereogenic center; (Diasteriomers)

Properties of enantiomers and diastereomers A) Enantiomers Have the same physical properties except for direction of rotation of plane polarized light Have the same chemical properties except for their reaction with other chiral molecules (This usually seen in their biological activity) B) Diastereomers Have different physical properties Similar chemical properties

Chemical reactions of stereoisomers 1) Generation of a chiral center

Reaction away from a chiral center

Generation of a second chiral center

Resolution of enantiomers Enantiomers + chiral molecules gives diasteriomers which can be sepearated, then we get red of the chiral molecules

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2025 SlidePlayer.com. Inc. All rights reserved.