Parkinson’s patient & physician aiding system Performed by: Alexander Kinko Stanislav Shapiro Barukh Trabelsi Instructor: Boaz Mizrachi

The Parkinson’s patient often suffers from involuntary seizures, that are unnoticeable to him, but tire his muscles and cause great pain. The appearance of the tremor is random. Muscles’ behaviour is very similar to that, as they were intensively used during some kind of hard work. Parkinson’s patient must have a periodic physiotherapeutic treatment, in order to relief the pain, caused by the cramped muscles. Patients can significantly improve quality of life, if were given some kind of an “alarm”, when the tremor starts. Consequently, the unwanted tremor can be stopped and the seizures of the muscles can be prevented. Introduction

Project’s Basic Concept PMD  PC Interface USER  PC Interface Parkinson’s Patient PMD – Parkinson Mobile Device (*) PC (*) - There are 2 versions of PMD developed: minimal/basic (small box) & enhanced (big box).

Design a portable low-power system which: Identifies presence of tremor. Analyzes vibrations and detects a Parkinson’s tremor. Notifies the user about appearing of unwanted tremor (“alarm”). Enables better tracking of the disease by storing data, describing specific tremor’s appearance, like:  Starting time  Duration  Strength (amplitude)  Frequency Runs on a daily basis, powered by rechargeable battery, that is recharged by the solar cells or by connection to the external power source. Low battery indicator alerts user when battery is low. Project’s Goals

Project’s Goals (continuation) Designing PCB and appropriate packaging, resulting in a small low-power Parkinson Mobile Device (PMD), like an ordinary wrist watch. Creating a unique set of software for PC and PMD, which enables performing of the following tasks:  Downloading data from portable device.  Performing of the data processing on downloaded data and displaying the appropriate statistics on PC.  Creating database and storing it for the further inspection by the patient / physician.

Recognition of a unique nature of Parkinson’s tremor (2÷12 Hz). Recognition of at least 2 Parkinson’s attacks per minute Storing parameters (starting time, duration, strength, frequency) describing each Parkinson’s attack in the non-volatile on-device memory. Optional notification to patient on appearing of Parkinson’s attack by:  Buzzer / LED indication  Vibration (enhanced system only) Interconnection to PC for performing extended data processing and better tracking. Functional Description Of The System

System’s Features Autonomous portable system, that can be worn on the Parkinson’s patient wrist. There’s an option, to put it on other patient’s limbs as well (head, leg, etc.). Both systems (minimal and enhanced) are small: minimal system – 15x32x52mm, enhanced system – 18x43x68mm. Minimal period for storing parameters - 7 days. Power supply by 3 different sources: solar cell, rechargeable battery and USB. “Low-battery” state alert. Communication with host PC by 2 different ways: IrDA & USB.

Functional Block Diagram Accelerometer Control Indication Patient PC - Doctor’s Application Parkinson’s Tremor PushbuttonsLEDsBuzzerVibration Motor Microcontroller Unit (MCU) PMD Doctor System Debug EEPROM System Power IrDA Transceiver IRUSB Modules marked with ‘---’ are different in basic & enhanced systems

FFT for 32 samples that were collected at 25Hz: * The x axis units are “resolution”: 1unit = 25/32 FFT Real Measurements Results