Practical Pathophysiology

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Presentation transcript:

Practical Pathophysiology Dr Tarek Atia

Brown atrophy of the heart: Sign of Cardiac aging

Atheroma of an Artery: atherosclerosis

Myocardial infarction 4

Wavy fibers is an early sign of myocardial infarction 5

Myocardial infarction: Coagulative necrosis and a few inflammatory cells 6

Myocardial infarction: Coagulative necrosis, interstitial bleeding, and a few inflammatory cells. 7

Dilated heart in myocarditis

Dilated cardiomyopathy

Cardiomyopathy (trichrome stain): extensive fibrosis (blue) between the myocytes. The myocytes also vary in size.

Hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy : myofiber dysarray ; not all fibers are pulling the same direction. Thus the contraction is ineffective.

Broncho-pneumonia 13

Lobar Pneumonia – Gray hep…

Bronchopneumonia 15

Lung Abscess: 16

Obstructive bronchus: chronic bronchitis or bronchial asthma

Bronchiectasis

Small cell carcinoma of the lung

Large Cell Carcinoma of the lung Bronchopneumonia

Minimal change disease Nephrotic Syndrome, Minimal change disease

Focal segmental glomerulosclerosis

Acute pyelonephritis with abscesses

Pyelonephritis

Adult polycystic kidney disease

Childhood polycystic kidney disease

Esophageal varices

Steatosis, fatty liver

Liver cirrhosis

Liver cirrhosis

Metastatic carcinoma, liver

Adenocarcinoma Liver

cervical squamous cell carcinoma

Invasive Cervical carcinoma

Fibroid uterus; Leiomyoma

Teratoma

Lobular Carcinoma

Atypical Hyperplasia

Schirrous Carcinoma

Fibrosis + Cysts = Fibrocystic Disease

Fibroadenoma

Atrophic mammary gland

Periductal Inflammation The tumor cells are INSIDE the skin dermal lymphatic spaces. Periductal Inflammation

Gynecomastia (NO Lobules) Note that no matter how big a male’s breasts may get, they should never for m lobules, but just end as blunt ducts. Gynecomastia (NO Lobules)

GOOD LUCK