Genotyping Results Each person was typed for 3 unlinked Short Tandem Repeat loci (STR) vWFII – chromosome 12, intron 40 of the vWF gene UT 2203 – chromosome 4, cM UT 1376 – chromosome 4, cM Individual genotyping results are in the MED2011_FALL_Genotypes.pdf file Allele frequencies for this class are compared to previous medical school classes and to other world populations using a neighbor-joining tree based on genetic distance estimates
Example – 3 STR markers UT , 288 UT , 202 vWFII 154, 162 A size marker (orange) is used to establish allele sizes STR Genotype bp Size ranges for all alleles bp bp vWFIIUT2203UT1376
Allele frequencies vWFIIUT2203UT1376 allele (bp) frequency
Genotype Summary and Sharing 83 Participants, 3 STRs vWFIICounts 154, , , , , , , , , , , , , , , , ,1743 No call9 UT2203Counts 199, , ,2029 No call11 UT1376Counts 281, , , , , , , , , , ,2971 No call21 3 Loci CombinedCounts 162,166199,199289, ,162199,202289, ,166199,202281, ,162199,202289, ,162199,199289,2892 No Call25 Unique45
Population Tree