What product would be obtained?. Hydroboration/oxidation is anti-Markovnikov addition of H and OH, but resulting enol tautomerizes to aldehyde. What product.

Slides:



Advertisements
Similar presentations
Aldehid dan Keton.
Advertisements

Bimolecular Elimination: E2 7-7 Strong bases effect bimolecular elimination. At higher concentrations of strong base, the rate of alkene formation becomes.
Aldehydes, ketones. Required background: Structure of alkenes Nucleophilic substitution S N 1, S N 2 Essential for: 1. Carboxylic aids and their derivatives,
Chapter 61 Reactions of Alkynes. Introduction to Multistep Synthesis Chapter 6.
© 2011 Pearson Education, Inc. 1 Organic Chemistry 6 th Edition Paula Yurkanis Bruice Chapter 19 Carbonyl Compounds III Reactions at the  -Carbon.
Chapter 9 Alkynes: An Introduction to Organic Synthesis
© Prentice Hall 2001Chapter 51 Hydrogen Halide Addition The addition of a hydrogen halide to an alkyne follows Markovnikov’s rule because a secondary vinylic.
1 Nucleophilic reactions involving enolate anions Aldehydes, Ketons and other carbonyl compounds having H on α-C -> in equilibrium (in solution) -> Keto-Enol.
Organic Chemistry William H. Brown & Christopher S. Foote.
© 2011 Pearson Education, Inc. 1 Chapter 10 Reactions of Alcohols, Amines, Ethers, Epoxides, and Sulfur-Containing Compounds Organic Chemistry 6 th Edition.
Alkynes Alkynes contain a carbon—carbon triple bond. Terminal alkynes have the triple bond at the end of the carbon chain so that a hydrogen atom is directly.
1 Alkynes contain a carbon-carbon triple bond. An alkyne has the general molecular formula C n H 2n−2, giving it four fewer hydrogens than the maximum.
Reactions of Alkenes. Some Reaction Types : Addition Elimination Substitution.
Alkynes.
Formation of glycols with Syn Addition Osmium tetroxide Syn addition also KMnO 4.
Carbonyl Compounds III
Alkynes. Structure sp hybridization Acidity of Terminal Alkynes Other strong bases that will ionize the terminal alkyne: Not KOH Stronger base Weaker.
Organic Chemistry 4 th Edition Paula Yurkanis Bruice Chapter 6 Reactions of Alkynes Introduction to Multistep Synthesis Irene Lee Case Western Reserve.
Nomenclature or names of compounds Alkanes. Nomenclature or names of compounds Alkanes.
ALCOHOLS Dr. Sheppard CHEM 2412 Summer 2015 Klein (2 nd ed.) sections 13.1, 13.2, 13.3, 13.5, 13.4, 13.6, 13.7, 13.10, 13.9,
Organic Chemistry Reviews Chapter 11 Cindy Boulton February 8, 2009.
Alkynes Reaction Acidity Synthesis.  Complex of Acetylene  Bonds.
111 Spring 2009Dr. Halligan CHM 236 Alkynes Chapter 11.
CHEMISTRY 2600 Topic #2: Electrophilic Addition Reactions of Alkenes and Alkynes Spring 2009 Dr. Susan Lait.
Chapter 11 Lecture Outline
Alkynes. Alkynes are molecules that incorporate a C  C triple bond.
Chapter 12 Alkene Reactions Part 2 I.Hydroboration—Oxidation A.Hydroboration 1)Borane, BH 3, is stable in ether or THF because they stabilize the Lewis.
John E. McMurry Paul D. Adams University of Arkansas Lecture 11 (Chapter 9) Alkyne Reactions.
Alcohols < < Nomenclature < < Properties < < Preparation < < Reactions < < Spectroscopy.
Alkyne Reactions I.Reduction of Alkynes A.Relative Reactivity of 2  -bonds Alkynes react like alkenes, but twice a)Hydrogenation of alkynes goes to alkanes.
© Prentice Hall 2001Chapter 31 Addition of Halogens The remaining halide ion is a good nucleophile which attacks the positively charged halonium ion.
CHEMISTRY 2600 Topic #3: Electrophilic Addition Reactions of Alkenes and Alkynes Spring 2008 Dr. Susan Lait.
IV. Oxidation Three types A. Epoxidation B. Hydroxylation C. Oxidative cleavage.
Organic Synthesis Reverse Synthesis. Always begin with the desired compound Deconstruct your desired compound using the organic synthesis flowchart word.
54c) Fill in the blanks f) j)
Chapter 11 Alcohols and Ethers
Carbonyl Alpha-Substitution Reactions
Learning Objectives Preparation of alcohols Intermolecular dehydration
Important Concepts12 1.Double Bond Reactivity – exothermic addition reactions leading to saturated products 2.Hydrogenation of Alkenes – immeasurably slow.
Properties of ,  -Unsaturated Aldehydes and Ketones 18-8 Conjugated unsaturated aldehydes and ketones are more stable than their unconjugated isomers.
126 Chapter 18: Enols and Enolates 18.1: The  -Carbon Atom and its pK a.
Organic chemistry for medicine and biology students Chem 2311 Chapter 9 Aldehydes and Ketones By Prof. Dr. Adel M. Awadallah Islamic University of Gaza.
Alcohols Biological Activity Nomenclature Preparation Reactions.
9.4 Hydration The components of water (-H and –OH) are added across a C=C double bond The acid catalyst is often shown over the arrow, because it is regenerated.
Reactions of aldehydes and ketones : oxidation reduction nucleophilic addition 1)Aldehydes are easily oxidized, ketones are not. 2)Aldehydes are more reactive.
1 1). 2 2) 3) 3 Ag 2 O and NH 4 OH are the Tollens reagent 4) 5)
Reactions of Alcohols, Amines, Ethers, and Epoxides
ALCOHOLS ETHERS & EPOXIDES. FUNCTIONAL GROUP  Alcohols contain a hydroxyl group (OH) bonded to an sp 3 hybridized carbon. The oxygen atom in alcohols,
Alkynes Introduction—Structure and Bonding
The next 2 slides are part of one question.. Which of the following is not a step in the mechanism of the given reaction?
1 כימיה אורגנית לתלמידי רפואה, מדעי הרפואה, ורפואת שיניים ד"ר עידית תשובה המחלקה לכימיה אי אורגנית בניין לוס-אנג'לס, חדר
Islamic University of Gaza
Ch 17- Carboxylic Acids and their derivatives
Chapter 11 Lecture Outline
Hydroboration-Oxidation of Alkynes
Electrophilic Substitution Reactions
Unit 0 Nomenclature.
Addition of H2O across a triple bond
Chapter 22 Carbonyl Alpha-Substitution Reactions
6.19 Epoxides – essential synthetic intermediates
Organic Chemistry, First Edition Janice Gorzynski Smith
Properties Nomenclature Preparation Reactions Synthesis
CH 12-3: Grignard Reaction-I
الفعل ورد الفعل ♠ ♠ ♠ مجلس أبوظبي للتعليم منطقة العين التعليمية
Alkynes: An Introduction to Organic Synthesis
Preparation of Alkenes
Organic Chemistry II Chapter 22 Carbonyl Alpha-Substitution Reactions
Mr. R. B. Gawade M. Sc. NET / GATE Assistant Professor in Chemistry
Chapter 23 Substitution Reactions of Carbonyl Compounds
Aldol reactions.
Presentation transcript:

What product would be obtained?

Hydroboration/oxidation is anti-Markovnikov addition of H and OH, but resulting enol tautomerizes to aldehyde. What product would be obtained?

Which would be the major product?

Hoffmann elimination – recall that cationic leaving groups favour this pathway, as do sterically small bases Which would be the major product?

What starting compound would you use for this reaction?

Meta-Chlorperoxybenzoic acid epoxidizes alkenes. What starting compound would you use for this reaction?

Choose the required reagent(s):