Biology 15, 03WProf. Gross Protein Structure and Function.

Slides:



Advertisements
Similar presentations
Protein Structure and Physics. What I will talk about today… -Outline protein synthesis and explain the basic steps involved. -Go over the Chemistry of.
Advertisements

1.The amino acid monomer. Spot the similarity.
NUCLEIC ACIDS {DNA;RNA} w 1. What are they? w 2. Where are they found? w 3. What are their functions? w 4. What is a nucleotide? Draw one. w (pages 219.
1 September, 2004 Chapter 5 Macromolecular Structure.
Introduction to Structural Bioinformatics Dong Xu Computer Science Department 271C Life Sciences Center 1201 East Rollins Road University of Missouri-Columbia.
Chapter 3 (part 2) – Protein Function. Test Your Knowledge (True/False) All proteins bind to other molecules. Explain. What sort chemical interactions.
1. Primary Structure: Polypeptide chain Polypeptide chain Amino acid monomers Peptide linkages Figure 3.6 The Four Levels of Protein Structure.
P247. Figure 9-1 p248 Figure 9-2 p251 p251 Figure 9-3 p253.
2.7 DNA Replication, transcription and translation
Objectives for protein section II Explain conformational changes in proteins. Explain how GTP binding & hydrolysis allows ras & other G-proteins to function.
Protein Modeling Challenge Science Olympiad Trial Event Shannon Colton, Ph.D., Event Supervisor Gary Graper, Event Technical Advisor.
Modeling Biomolecules Using the WWW. Major Classes of Biomolecules n Peptides (Proteins) n Carbohydrates n Nucleic Acids n Lipids.
Lab 2: Organelles, Proteins, and SDS-PAGE
3-Dimensional Structure of Proteins 4 levels of protein structure:
Lipids.  A class of molecules that is hydrophobic  Hydrophobic= water fearing Ex.  Fats  Oils  Steroids.
Protein Structure and Function 1 , 2 , 3 , 4  Structure Viewing, interpreting structure Protein Characterization BIO520 BioinformaticsJim Lund.
Macromolecules Review
Objectives E – Recall the different structures of proteins and the test for proteins. C – Describe how a peptide bond is formed. Describe the different.
Protein Synthesis (Eukaryotes)
Comparison of p53 Structure: Wild type vs. mutant What change in wild type p53 may lead to cancer?
Protein Modeling Challenge Science Olympiad Trial Event Gary Graper, Event Supervisor Shannon Colton, Ph.D., Event Technical Advisor Jennifer Morris, Ph.D.,
Companion site for Biotechnology. by Clark Copyright © 2009 by Academic Press. All rights reserved. 1 Introduction of Disulfide Bonds A disulfide bond.
Quiz (take out a sheet of paper 1. T/F DNA can exit the nucleus 2. Name the bases found in RNA 3. Name the enzyme used to construct RNA during transcription.
 DNA must be copied (before a cell divides)  The DNA molecule produces 2 IDENTICAL new complementary strands following the rules of base pairing: A-T,
Protein Synthesis Occurs in 2 steps – Step 1: Transcription Taking DNA and transcribing it into RNA – Step 2: Translation Taking RNA and translating it.
Proteins & DNA. Amino Acids: the building blocks of Proteins.
Conserved features of protein-DNA interaction in all X-ray characterized families of DNA-binding proteins N.N. (GI/MR/M) / N.N. (GI/MR/M) Introduction.
Mrs. Einstein Research in Molecular Biology. Importance of proteins for cell function: Proteins are the end product of the central dogma YOU are your.
1 P8 Extra Discussion Slides. Visualization of 3-D structure PyMOL is a tool/software that helps with the visualization of 3D structure PyMOL does not.
Proteins Pgs Pgs Allosteric Enzymes  Allosteric enzymes have 2 sites. Active site of the enzyme Additional site where another substance.
Protein synthesis Lesson 6 GCSE Triple Science Module 14.
PROTEINS The final product of the DNA blueprint Hemoglobin.
Below is the database schema used by the RCSB Protein Data Bank Each box indicates a separate attribute set Bioinformatics databases are very large PROTEIN.
Protein Structure Primary - sequence of amino acids Secondary – folding into pleated sheets or alpha helix Tertiary – 3-D structure, completely folded.
Protein Structure  The structure of proteins can be described at 4 levels – primary, secondary, tertiary and quaternary.  Primary structure  The sequence.
Proteins Clicker. The molecules marked “W” are best described as: 1.Monomers 2.Polymers 3.Isomers 4.isotopes.
1 2. Nucleic acids and proteins in one and more dimensions.
What is a macromolecule? There are four main types of biological molecules called macromolecules. The four types of macromolecules are carbohydrates, lipids,
3S: Proteins Shireen Rudina. What do proteins do? Structure – Collagen in skin, keratin in hair and nails Signaling between cells Defend against disease.
Membrane Protein Structure Prediction and Visualization Chuck Staben Jerzy Jaromczyk.
Aldehyde Dehydrogenase Zach Lawton 1. Background Superfamily of Nictonamide adenine dinucleotide phosphate (NADP) enzymes Location: all three domains.
BIO409/509 Cell and Molecular Biology.
Proteins   One of the most important organic molecules   Almost 50% dry weight of cells   Composed of monomers known as amino acids   Contains.
Proteins.
Concept 16.3 A Chromosome consists of a DNA molecule packed together with proteins The bacterial chromosome is a double-stranded, circular DNA molecule.
Jumpstart #???? 1) Draw the Lewis dot diagram of NH3
Chemsheets AS006 (Electron arrangement)
Introduction of Disulfide Bonds
Protein Synthesis and Protein Folding
Make Your Own Quiz.
. Nonpolar (hydrophobic) Nonpolar (hydrophobic) Amino Acid Side Chains
Quiz #7 (8%) Biol710 11/21/12 name___________
3. Proteins Monomer = Amino acids Globular in shape Or Spherical.
Figure 3.14A–D Protein structure (layer 1)
TRANSCRIPTION FLOWCHART
Amino Acids.
פחת ורווח הון סוגיות מיוחדות תהילה ששון עו"ד (רו"ח) ספטמבר 2015
Study Question: What are enzymes?
Enzymes and Proteins.
بیوشیمی : پروتئین ها و لیپیدها
Honors Biology Monkemeier Friday, January 18, 2019
HLA-A Disparities Illustrate Challenges for Ranking the Impact of HLA Mismatches on Bone Marrow Transplant Outcomes in the United States  Lee Ann Baxter-Lowe,
Transcription Initiation at Its Most Basic Level
Tauomics and Kinetics in Human Neurons and Biological Fluids
(Really) Basic Molecular Biology
1. It is made up of Monosaccharides
FIGURE 8.1. Overview of protein synthesis.
Volume 2, Issue 1, Pages 1-4 (January 1994)
Presentation transcript:

Biology 15, 03WProf. Gross Protein Structure and Function

Biology 15, 03WProf. Gross Figure 2-19

Biology 15, 03WProf. Gross Figure 2-20

Biology 15, 03WProf. Gross Panel 2-5

Biology 15, 03WProf. Gross Panel 2-5

Biology 15, 03WProf. Gross Panel 2-5

Biology 15, 03WProf. Gross Panel 2-5

Biology 15, 03WProf. Gross Panel 2-5

Biology 15, 03WProf. Gross Figure 5.2

Biology 15, 03WProf. Gross Figure 5.4

Biology 15, 03WProf. Gross Figure 5.5

Biology 15, 03WProf. Gross Figure 5.6

Biology 15, 03WProf. Gross Figure 5.8 Size Distribution of Proteins

Biology 15, 03WProf. Gross Figure 5.9 Alpha Helix

Biology 15, 03WProf. Gross Figure 5.9 Beta Sheet

Biology 15, 03WProf. Gross Figure 5.10

Biology 15, 03WProf. Gross Figure 5.11

Biology 15, 03WProf. Gross Figure 5.12 DNA binding domain cAMP binding domain

Biology 15, 03WProf. Gross Figure 5.14

Biology 15, 03WProf. Gross Figure 5.15

Biology 15, 03WProf. Gross Figure 5.17

Biology 15, 03WProf. Gross Figure 5.17

Biology 15, 03WProf. Gross Figure 5.18

Biology 15, 03WProf. Gross Figure 5.21 CollagenElastin

Biology 15, 03WProf. Gross Figure 5.22

Biology 15, 03WProf. Gross Some Resources Bio 15 web site CHIME installer RASmol Amino Acid Quiz Protein Data Bank (PDB)PDB Protein Explorer Website