Specie: Anopheles gambiae PEST Genome size: 260 Mb Status: 3rd assembly and annotation NIAID funded.

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Presentation transcript:

Specie: Anopheles gambiae PEST Genome size: 260 Mb Status: 3rd assembly and annotation NIAID funded

Species: Aedes aegypti Liverpool Genome size: 1.3 Gb Status: 1st assembly and annotation NIAID funded

Species: Culex pipiens quinquefasciatus JHB Genome size: 540 Mb Status: Shotgun sequencing completed ~8 X NIAID funded

Species: Ixodes scapularis WIKEL Genome size: 2.1 Gb Status: Shotgun sequencing in progress ~4 X NIAID funded

Species: Peduculus humanus humanus Genome size: 100 Mb Status: Shotgun sequencing completed, ~8 X NHGRI funded

Species: Glossina morsitans morsitans Genome size: Mb (~7 Gb ??) Status: ~3 X coverage approved, > 40 K EST available Sanger Center

Species: Phlebotomus papatasi, Lutzomyia longipalpis Genome size: Pp, ~170 MB, Ll ~ 300 Mb Status: BAC end and ESTs in progress, > 30 K EST avail. NHGRI and Sanger Center

Species: Rhodnius prolixus Genome size: 670 Mb Status: Preliminary analysis of genomic DNA NHGRI funded

Species: Anopheles gambiae M and S Forms (6-10 other Anopheles spp. pending) Genome size: 260 Mb Status: Shotgun sequencing in progress NHGRI funded

Genome-specific Curation Anopheles gambiae PEST - Kitsos Louis Aedes aegypti - Neil Lobo Culex pipiens - Peter Arensburger Ixodes scapularis - Cate Hill Anopheles gambiae M/S - Nora Besansky Other species - lead authors of white papers

Discussion of Morning Topics 1.Too many genomes 2.VectorBase web site view 3.VectorBase web site content 4.AnoBase integration 5.EST data independent of genomes 6.CVs 7.Expression/array data

Population Data 1.Insecticide resistance data: High priority, directly linked to genomes 2.Population genetics data: Marker sets and population genetics data sets, directly linked to genomes 3.Population genetics of other species for which genomes are not available 4.Epidemiological/Ecological data: Parallel development by malaria groups in Africa 5.Vector and parasite population data

Malaria Monitoring and Control Consortium (BMGF) Malaria vector transmission and ecology data from 6 countries Core malaria vector data sets to drive malaria simulation models BMGF and MMCC objective of common data repository and format

Population Data versus Genome Data

Specie: Sabethes cyaneus Genome size: Status:

Specie: Trypteroides bambusa Genome size: Status:

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