The following slides present some answers….. Please don’t peek before doing the exercise!

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Presentation transcript:

The following slides present some answers….. Please don’t peek before doing the exercise!

Flavodoxin family - TOPS diagrams (Flores et al., 1994)

Flavodoxin fold: aligning 13 Flavodoxins + cheY 5(  ) fold

Protein structure evolution Insertion/deletion of secondary structural elements can ‘easily’ be done at loop sites Can you see this happening at the earlier TOPS slide?

Protein structure evolution Insertion/deletion of structural domains can ‘easily’ be done at loop sites N C This is for later……