Protein Activity Unmasked

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Presentation transcript:

Protein Activity Unmasked By Christopher Rusnak

DNA→RNA→Protein DNA RNA Protein Alberts et al.: Molecular Biology of the Cell , fourth edition, Garland Science, 2002. "DHSAPBIO » Blog Archive » Nucleic Acids." IBlog | Home. Web. 06 June 2011. <http://blog.dearbornschools.org/renkomapbio/2010/10/17/nucleic-acids/>. Griffiths, AJF. "Gene-protein Relations." An Introduction to Genetic Analysis. 7th ed. NIH, 2000. Web. 6 June 2011. <http://www.ncbi.nlm.nih.gov/books/NBK21811/>.

Levels of Protein Structure SIKKRFRMYILISIISASLDYKSAAIDIRERFSY HHHHHHCCEEEEEECCCCCCEEEEEEEECC "Module 3: Basic Science, Biology Core." ABCTE | Get Certified and Become a Teacher. ABCTE, 2007. Web. 06 June 2011. <http://www.abcte.org/files/previews/biology/s3_p2.html>. "File:Protein Primary Structure.svg." Wikipedia, the Free Encyclopedia. Web. 06 June 2011. <http://en.wikipedia.org/wiki/File:Protein_primary_structure.svg>.

Levels of Protein Structure Home Page. Web. 06 June 2011. <http://andersonlab.qb3.berkeley.edu/Tutorials/Bare_Bones_Biochemistry.htm>. "RCSB PDB - 3A0I Structure Summary." Web. 06 June 2011. <http://www.rcsb.org/pdb/explore/explore.do?structureId=3A0I>.

SNAP and Neural Networks 1. "Neural Networks in Plain English." Welcome. Web. 06 June 2011. <http://www.ai-junkie.com/ann/evolved/nnt4.html>. 2. SNAP: predict effect of non-synonymous polymorphisms on function. Yana Bromberg and Burkhard. Rost Nucleic Acids Research, 2007, Vol. 35, No. 11 3823-3835

Goal of Research Bromberg et al. "In Silico Mutagenesis: a Case Study of the Melanocortin 4 receptor." The FASEB Journal (2009). Web. Welcome to Rost Lab: ROSTLAB.ORG. Web. 06 June 2011. <http://rostlab.org/services/snap/HXK4_HUMAN.all>.