Monday 9:00 – 13:00 - Group Break 11:25 – 11:45 14:00 … Optional individual consultation Tuesday 9:00 – 13:00 – Group Break 11:25 – 11:45 14:00 … Optional individual consultation Wednesday: Optional individual consultation

Workshop Overview 1.Obtaining 3D Macromolecular Models 2.Understanding The Models 3.Sharing Structure-Function Information Martz – May 2010

Workshop Overview 1.Obtaining 3D Macromolecular Models a)Published Empirical (Crystallographic or NMR) b)Homology Models (Theoretical Models Are Grossly Inaccurate) 2.Understanding The Models 3.Sharing Structure-Function Information Martz – May 2010

Workshop Overview 1.Obtaining 3D Macromolecular Models 2.Understanding The Models a)Proteopedia b)FirstGlance in Jmol ( + links to Key Resources) 3.Sharing Structure-Function Information Martz – May 2010

Workshop Overview 1.Obtaining 3D Macromolecular Models 2.Understanding The Models 3.Sharing Structure-Function Information: Custom Molecular Scenes without Tears a)Proteopedia: a wiki; rotating molecules; on-line b)Polyview-3D: publication quality; animations for Powerpoint Martz – May 2010

Gal 4 Transcriptional Regulator Protein. DNA Double Helix (Chain / Chain). Lysine 18 sits in DNA Major Groove recognizing CGG. Martz – May 2010 – 1d66

Animation Created by Polyview-3D (using PyMOL) Martz – May 2010 – 1d66