Neurological Emergencies Treatment Trials SAEM 2006.

Slides:

Advertisements

Similar presentations

Retreat Topics iPSC Opportunities in NIAMS Diseases Science Management Forum: Leveraging and Strategic Funding Collaborations Atopic Dermatitis Advancing.

Advertisements

Health Services Research Howard Bailit, DMD, PhD University of Connecticut Dental Informatics and Dental Research Conference National Institutes of Health.

NETT Financial & Subcontract Tele-conference Agenda October 11, 2007 Overview of the NETT CCC-hub agreements and formats utilized (PSA vs. FDP) –

?? Collaborations for hypothermia research ?? Target disorder Different technologies Treatment protocols Basic/translational/clinical.

Component 2: The Culture of Health Care Unit 4: Health care processes and decision making Lecture 1 This material was developed by Oregon Health & Science.

Helena Chui, M.D. McCarron Professor and Chair of Neurology Director, Alzheimer Disease Research Center.

Health Line of Business Revised Health Domains January 26, 2005 Outcomes / Domains have been revised.

YALE MASTER SLIDE HERE Clinical Research Management – Is not just a handshake deal? Jamie Caldwell, MBA Director Office of Research Services for the Health.

Neurological Emergency Treatment Trials Network Overview of the new network nett.umich.edu.

NETT NETWORK CLINICAL COORDINATING CENTER University of Michigan University of California San Francisco University of Cincinnati.

Andy Jagoda, MD, FACEP The Role of Emergency Medicine in Neurologic Emergencies Andy Jagoda, MD, FACEP Professor of Emergency Medicine Mount Sinai School.

Neurological Emergency Treatment Trials Network Overview of the new network William Barsan, MD PI—NETT CCC nett.umich.edu.

Edward P. Sloan, MD, MPH, FACEP Successful Grantmanship Government Grant Writing & the PHS 398 Form.

Research Project Idea Generation: So Much to Do, So Little Time.

Templates for Organizing Stroke Triage. Getting Started Physicians Hospital administration Medical Society Hospital Council Stroke survivor groups Other.

The NIH Roadmap for Medical Research

Acute Ischemic Stroke Management: 2004 Emergency Medicine Perspectives.

Collaborative Mental Health Care Pilot Program Bidder’s Conference October 27, 2014.

Johns Hopkins Technology Transfer 1 Translational Biomedical Research: Moving Discovery from Academic Centers to the Community Translational Biomedical.

Mike Conlon Here’s Mike on a conference call from his home. Mike spends a lot of time on conference calls from his home, and from coffee shops in and around.

9/17/ Access WHI: Proposing Analyses and Ancillary Studies Andrea Z. LaCroix, PhD Professor of Epidemiology and Co-PI WHI Clinical Coordinating Center.

Quality Improvement Project March Now Future.

Newborn Screening Translational Research Network Coordinating Center Duane Alexander, M.D. Director, Eunice Kennedy Shriver National Institute of Child.

Occupational Medicine Recognized Specialty Since 1949 Combines Clinical Skills With Toxicology, Epidemiology, Safety, Rehabilitation, and Business Operations.

Diabetes Control and Complications Trial (DCCT) Results indicate that most youth with T1DM should be treated intensively in order to reduce the risk of.

Anticipated FY2016 Appropriations Agency$ Million NIH200 Cancer70 Cohort130 FDA10 Office of the Natl Coord. for Health IT (ONC) 5 TOTAL215 Mission: To.

Indiana Institute For Personalized Medicine David A Flockhart MD, PhD Professor of Medicine, Genetics and Pharmacology Indiana University.

Hospital Categorization: Role in Advancing Emergency Medicine Track D September 15, 2003 Barcelona Lewis R. Goldfrank, MD Professor and Chairman of Emergency.

U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES FITBIR: A Platform for International.

Architecture Design of Generic Outcome Adjudication in CTMS Wenle Zhao, PhD Medical University of South Carolina, Charleston, SC, 29425, USA Society for.

RESEARCH PROGRAM UPDATE Sarah Castro, MPH Senior Research Support Liaison.

Cancer Centers In Clinical Trials Sandrine Marreaud Head of Medical Department.

National Center for Research Resources G. Iris Obrams, M.D., M.P.H., Ph.D. NCRR Update 5 August 2006.

The Wisconsin Network for Health Research (WiNHR): Overview. An Infrastructure for Conducting Multi-Site Clinical Research across the State of Wisconsin.

SAEM and Mentorship in Academic Emergency Medicine Andra L. Blomkalns, M.D. Vice Chair, Department of Emergency Medicine University of Cincinnati College.

Research How-To’s in a Community Setting Gregory W. Heath, DHSc, MPH Director of Research.

Design of Patient-Centered Care Health IT Patient Advisor involvement in ePHR Design and Outcomes Research Patricia Sodomka, FACHE Senior Vice President,

Research Priorities & Trends for NIH in 2003 Claire T. Driscoll Director Technology Transfer Office National Human Genome Research Institute (NHGRI) Research.

Reasons Why Referral process critical issue Need for engagement, connecting the system Community building: innovation, adaptation, learning Locally grown.

ICARE Member Reports National Institutes of Health/National Institute of Neurological Disorders and Stroke NIH Mission: NIH is the steward of medical and.

Michael J. Bell, MD Stephen R. Wisniewski, PhD University Of Pittsburgh National Institute Of Health National Institute Of Neurological Disorders And Stroke.

An Advertisement from the Program Director Alice Ma, MD

Health Resources and Services Administration- Oral Health Update American Association of Community Dental Programs Renée W. Joskow DDS, MPH Senior Dental.

“Translational research includes two areas of translation. One (T1) is the process of applying discoveries generated during research in the laboratory,

Neurological Emergency Treatment Trials Network Six questions about the new network Robert Silbergleit, MD University of Michigan.

Alberta Health Services Strategic Clinical Networks: an opportunity for KT research? David W. Johnson Alberta Children’s Hospital.

Study Design: Making research pretty Adam P. Sima, PhD July 13, 2016

MedStar Health Research Institute

Is Telemedicine Still the Appropriate Resource for Triaging Stroke Transfers? Good morning Adrienne and I review telestroke data every month and as we.

Jim Bland Executive Director, CRIX International

Foundational services in a metro health department

The Essentia Institute of Rural Health (EIRH) is

Solutions to Clinical Data Visualization and Analysis

Strategic Planning Process

Clinical Trial Budgeting

Strategic Planning Process

Improving Access to Subspecialty Care in an Academic Medical Center

CSS Clinical Trial Launched: January 2018

South Texas Oral Health Network (STOHN) & the Tooth Fairy Project

Rare Diseases Research: From Study Budgets to Patient Recruitment

JH Trial Innovation Unit (TIU)

Trial Innovation Network A new national collaborative initiative within the CTSA Program and is composed of three key organizational partners – the CTSA.

Mapping Sponsored Collaborations

Strategies to Innovate EmeRgENcy Care Clinical Trials Network SIREN

Medical Research Funding and Regulation Third Annual Medical Research Summit March 6, 2003 Mary S. McCabe National Institutes of Health.

Clinical and Translational Science Awards Program

Experimental Medicine Challenge Grants Round 3

Trial Funding and Engagement: The NIH Sponsored CTSA Program

Institute for Advanced Clinical Trials for Children

National Pediatric Critical Care Collaborative Research Network

Presentation transcript:

Neurological Emergencies Treatment Trials SAEM 2006

Disclaimer We don’t have authoritative answers to any of your questions We have applied to be the Clinical Coor- dinating Center for this application, but this has not been awarded to anybody yet We do not represent the NINDS or any agency here, we are just sharing personal opinions based on having thought a lot about this network

History Oct first organizational NET*2 meeting Mar 2004 – NIH conference on ENTCN NET*2 investigator initiated planning and pilot trial grant applications / surveillance Nov 2005 – RFA for NETT Coordinating Center Apr 2006 – RFA for NETT Hubs and SDMC

Defining Principals Set forth by NINDS Very early enrollment Diverse enrollment, hub and spoke design Large simple trials

Operational Principals Our vision Streamlined operations Technological efficiencies when possible Centralized outcome assessments Clinical translation

Impact Opportunity to advance care of patients with neuro-emergencies Large NIH investment in emergency medicine clinical research Re-engineering the clinical research enterprise

What does an application need? We don’t really know Enrollment Experience Collaboration

Enrollment Sufficient patient volume Access to diverse diagnoses –Adults and children –Neurotrauma, TBI and SCI –Stroke, ischemic and hemorrhagic –Seizure, meningitis, anoxic injury Local infrastructure

Experience ED clinical trials (any disease) Institutional track record Cross disciplinary research

Collaboration Emergency Medical Services Spokes –Diversity –Buy in Cross disciplinary –Emergency Medicine –Neuro-Critical Care –Neurology / Neurosurgery –Trauma surgery

Spokes Don’t have to use all spokes for all trials Look for areas of concentration –Trauma –Stroke –EMS expertise

Budget suggestions Include all effort needed to: –Set up the program –Prepare potentially complex IRB apps –Enroll subjects in two trials, best guess –Collect and report data –Provide informatics support Include –Travel to investigator meetings

Budget suggestions

Resources RFA for the 3 components ENCTN final report UM CCC application Links to all available at