Chapter 16 (Part 3) Fatty acid Synthesis.

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Presentation transcript:

Chapter 16 (Part 3) Fatty acid Synthesis

ACP vs. Coenzyme A

Fatty Acid Synthesis Occurs in the Cytosol Citrate synthase Citrate Lyase Malate dehydrogenase Malate Enzyme Pyruvate carboxylase

Acetyl-CoA Carboxylase Acetyl-CoA + HCO3- + ATP  malonyl-CoA + ADP

Acetyl-CoA Carboxylase

Regulation of Acetyl-CoA Carboxylase (ACCase)

Animal Fatty Acid Synthase

Further Processing of Fatty acids: Desaturation and Elongation

Allosteric regulation of fatty acid synthesis occurs at ACCase and the carnitine acyltransferase

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