Dermatomes overlap Skin Peripheral nerve Dorsal root Ventral root
Dermatomes overlap Skin Peripheral nerve Dorsal root Ventral root
Spinal cords Dorsal column Dorsal root ganglion Lateral column “Anterolateral” column Ventral column Dorsal root Spinal nerve Dorsal horn Intermediate zone Ventral horn Ventral root Spinal cords
Receptor projections to systems Bare nerve ending Anterolateral system Merkel’s receptor Meissner’s corpuscle Pacinian Dorsal column- medial lemniscal system Receptor projections to systems
Reminder: Rexed’s laminae LgTermPatterns
DC lesion Somatotopic organization of the dorsal columns Rostral Demyelination Caudal DC lesion
Lamina 5 Lg&SmTermPatterns
Lamina 5 Lg&SmTermPatterns
Anterolateral system X
Spinal Hemisection Ipsilateral loss of touch… Contralateral loss of pain… (2-3 segments caudal to injury) Mechanoreceptor Nociceptor
Syringomyelia • Bilateral loss of pain & thermal senses Site of lesion • Bilateral loss of pain & thermal senses • Preservation of mechanosensations
Somatotopy of spinal paths
Dorsal column-medial lemniscal system Anterolateral system Dorsal column-medial lemniscal system Postcentral gyrus / 1° SScx Postcentral gyrus / Insular/ Cingulate cortex Dorsal column nuclei Dorsal horn Also: •Reticular formation •Superior colliculus (mesencephalon) Spinal commissure Internal arcuate fibers Pain, thermal, itch Mechano…
Somatic Sensory Thalamus Medial dorsal Ventral posterior (VMpo) Ventral posterior medial-VPM (trigem) Ventral posterior lateral-VPL (spinal) Touch Pain
Leg area Arm area Face area Internal capsule Ventral posterior nucleus