University of Ghent, 2000 Alfonso Valencia %identity with a protein of known structure 0%0% 100 % 30 % Homology modeling Threading Ab initio 3D Structure.

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University of Ghent, 2000 Alfonso Valencia %identity with a protein of known structure 0%0% 100 % 30 % Homology modeling Threading Ab initio 3D Structure prediction

University of Ghent, 2000 Alfonso Valencia Protein fold recognition by prediction-based threading "TOPITS". Rost, Schneider, Sander (1997) J. Mol. Biol. 270, Secondary structure prediction Prediction- based threading

University of Ghent, 2000 Alfonso Valencia Pazos, Rost, Valencia 1999 Threadlize Interactive inspection and manipulation of threading models

University of Ghent, 2000 Alfonso Valencia

University of Ghent, 2000 Alfonso Valencia Plotcor r Pazos, Olmea & Valencia, 1997

University of Ghent, 2000 Alfonso Valencia Sequence features related to structure and function

University of Ghent, 2000 Alfonso Valencia CASP2 (1997) Fold Recognition (Threading)

University of Ghent, 2000 Alfonso Valencia CASP3 (1999). Threading.

University of Ghent, 2000 Alfonso Valencia CASP4 (2000): our predicitons by D. Devos

University of Ghent, 2000 Alfonso Valencia - Threading prog. Score - Cons. Res. Closeness. - Tree-det " - Corr. Mut " - Apolar res. " - Fold compactness - Fold predicted by diff. Threaders. Threadin g model

University of Ghent, 2000 Alfonso Valencia Threading server. Proc. Control: Flowchart CGI Start Parameter Checking Valid address 'Threadable' seq. Valid seq. format Fork & Detach Threaders Launching Threader 2 PredictProtein 3D-PSSM SAM-T98 HMM ERROR!!! Aborting... Sleep Check Match & SaveDiscard Follow, TimeOut or Finish Threader 2 PredictProtein 3D-PSSM SAM-T98 HMM Run Threadlize PostProcessing Send Results or Full Working tree by J.M. Fernández

University of Ghent, 2000 Alfonso Valencia Threading server methods by F. Pazos

University of Ghent, 2000 Alfonso Valencia by F. Pazos CAFASP2 (2000) Servers for Automatic Structure Predictions

University of Ghent, 2000 Alfonso Valencia