GI Sequence - Histology Small and Large Intestines Recto-anal junction January 14, 2009 Sun-Kee Kim / Andy Chervenak.

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GI Sequence - Histology Small and Large Intestines Recto-anal junction January 14, 2009 Sun-Kee Kim / Andy Chervenak

#29 Small Intestine Mesentery (ct + epithelium) Submucosa (connective tissue) Mucosa (epithelium + lamina propria) Muscularis Externa (smooth muscle) Lumen Muscularis mucosae

#29 – Intestinal Villi Intestinal villi

#29-Simple columnar epithelium with striated border (microvilli) and goblet cells Microvilli (striated border) Goblet cells Enterocytes ?

#165 (PAS)-Goblet cells distributed throughout villi and crypts

Pyloric Stomach Pylo-duodenal junction (arrow) Pyloric sphincter muscle

#161 Pylo-duodenal J. with Pancreas Pyloric stomach Duodenum Pancreas

#161 Muscularis mucosae Lymphatic nodules Brunner’s gland

#161, 162 Duodenum Lumen Intestinal villus Muscularis mucosae ? ? crypts or i. glands Brunner’s glands pancreas

#29, 168, 169, 170 Jejunum or Ileum lumen submucosa Muscularis mucosae Crypts of Lieberkuhn

#29, Intestinal glands (crypts) Paneth cells Enteroendocrine cells Mitotic cell ? ? ?

#246 Enteroendocrine cell Paneth cell

#29, Myenteric (Auerbach’s) plexus Ganglion cells

#176, 177: Colon (Mucosa of the colon) m.m No villi, Straight glands, lots of goblet cells

#176 – colon mucosa

#175: Appendix Mucosa is like colon: no villi, straight glands Muscularis externa is like small intestine: Two layers of s. muscle Heavy infiltration of lymphatic tissues forming nodules.

#177-1, 177-3, Recto-anal junction Hemorrhoidal veins Muscularis mucosae Type of epithelium changes Muscularis mucosae frays Dilated veins

#177-1, 177-2, Recto-anal junction Internal anal sphincter (sm. muscle) External anal sphincter (skel. muscle) Hair follicle w/ sebaceous and sweat glands

Cardio-esophageal junction (arrow)

Chief cells Paneth cellsParotid gland acinar cells von Ebner’s gland Mixed salivary glands Serous acinar cells Serous demilune cells

#170 Small Intestine

#194 Gallbladder Mucosa epithelium lamina propria Smooth muscle Adventitial c.t. Liver Simple columnar ep.