IEG - Arc/Arg 3.1 Allatostatin receptor (AlstR) + 10 nM Alst GFP controlled by Arc/Arg 3.1 gene promoter Genetical strategy for silencing a memory-encoding hippocampal cell assembly

Erasing and re-installing a hippocampus-dependent memory

Behavioural protocols and `high-cost decision point´

14-tetrode microdrive64 channel Neuralynx Cheetah system Extrafield firing at the high-cost decision point

Nonlocal representations at the choice point preferentially sweep forward of the animal Nonlocal representations at the choice point sweep down the two choices separately

Extrafield firing during error correction

Nonlocal representations are correlated but not defined by the orientation of motion Nonlocal representations occur at locations of highly variable orientation of motion Difference between histograms of reconstruction error distance during samples with variable orientation of motion and during the rest of the session.

High theta power at the choice points, no SW ripples.

The total amount of nonlocal reconstructed probability decreased multiple-T task In contrast, on the cued-choice task, the forward component of the sweep maintained nonlocality. Development of nonlocal representations with experienceSplitter cells – unindentified extrafield firing of place cells

hippocampus ventral striatum orbitofrontal cortex (only the prediction component) (reward anticipation) (the value of potential choices) prefrontal cortex (decision making parameters) “vicarious trial and error” (VTE) behaviors behavioral “microchoices” VTE Hippocampal reevaluation in spatial navigation

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