(-)-Kendomycin 2009.05.18 Angew. Chem. Int. Ed. 2009,48,()

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Presentation transcript:

(-)-Kendomycin Angew. Chem. Int. Ed. 2009,48,()

1. Macrocyclic polyketide isolated from different Streptomyces species in Endothelin receptor antagonist. 3. Antiosteoporotic agent. 4. Remarkable antibacterial (MRSA) and cytostatic activity. 5. Four total synthesis and one formal synthesis

Seyferth-Gilbert homomogation J. Chem. Soc. Chem. Commun. 1973, 151.

Schwartz Hydrozirconation

Fries-, photo-fries and anionic ortho-fries rearrangement

J. Org. Chem., 1997, 62 (19),

Amos B. Smith, 3. J. AM. CHEM.SOC.2005,127, ,128,

Chulborn Lee. J. AM. CHEM. SOC. 2004, 126,

OL, 10(17),

J. Am. Chem. Soc., Vol. 122, No. 40, 2000, 9837

Barbier coupling reaction

Scott D. Rychnovsky J. AM. CHEM. SOC. 2008, 130, 13177–13181

Chem. Commun., 2006, 2388–2390

谢谢 !