Cutaneous Manifestation of Cardiovascular Disease Done by Mohammad Binhussein

Dermatologists may be the first physician to diagnose an underlying cardiovascular disease

skin findings in addition to general dermatologic signs suggestive of cardiovascular disease 1.Infective endocarditis 2.Acute rheumatic fever 3.Cholesterol embolization syndrome 4.Lipid disorders 5.Kawasaki disease 6.Pseudoxanthoma elasticum

Infective endocarditis Osler nodes

Infective endocarditis Janeway lesions

Risk Factor? heart valves degenerative valve disease prosthetic valves intravenous drug use recent cardiac or dental surgery mitral valve prolapse and rheumatic heart disease

Causative Organism? Usually caused by viridans streptococci & staphylococci

postinfectious sequela of a group A β-hemolytic streptococcal pharyngitis Acute rheumatic fever

Erythema marginatum

Cholesterol embolization syndrome Livedo reticularis

Describe? red or blue, mottled, netlike discoloration

Xanthelasma Lipid Disorder

soft yellow macules or plaques Describe?

Premature development may indicate familial hypercholesterolemia

Pseudoxanthoma elasticum

genetic disorder of connective tissue affecting the skin, eyes, and cardiovascular

plucked chicken skin

Kawasaki

immune-mediated vasculitis mucocutaneous lymph node syndrome fever lasting 5 or more days without explanation combined with at least 4 of the 5 principal clinical features, as follows: (1) bilateral conjunctival injection, (2) oral mucous membrane changes, (3) peripheral extremity changes, (4) polymorphous rash, and (5) cervical lymphadenopathy

LEOPARD syndrome

The lentigines are dark brown irregularly shaped macules ranging in size from pinpoint to 5 cm with involvement of the face, neck, and upper trunk

Cardiocutaneous lentiginosis syndrome and multiple lentigines syndrome, is an autosomal dominant disorder of variable penetrance stands for Lentigines, ECG changes, Ocular telorism, Pulmonary valve stenosis, Abnormal genitalia, Retardation of growth, and Deafness.