Chapter 43 Amines

Purpose The object of this experiment is to identify an unknown amine or amine salt. First test to employs checking of solubility. Second experiment represents a Hinsberg test for distinguishing between primary, secondary and tertiary amines.

Hinsberg Test In Hinsberg test, the sulfonamides are distinguishable because the derivative from a primary amine has an acidic hydrogen, which renders the product soluble in H2O. Whereas the sulfonamide from the secondary amine is insoluble.

Comments Follow pp. 588-590 (microscale). Follow the lab handout for all experimental procedures. Wearing rubber gloves is necessary during this lab. You will work with toxic and corrosive compounds. Use solubility and Hinsberg test to figure out the unknown structures.

Safety Amines are toxic and have a characteristic smell: work in the hood. Do not swallow, do not inhale and avoid contact with eyes and skin. Wear gloves and handle with caution. Benzenesulfonyl chloride is corrosive, avoid contact with skin and eyes, wear gloves and goggles, use caution.