Chapter 11: Biological Membranes and Transport. Membranes are much more than just phospholipid.

Slides:

Advertisements

Similar presentations

Molecular Basis of Membrane Transport

Advertisements

In active transport, energy is used to move a solute against its concentration gradient. For each molecule of ATP used, 2 K + are pumped into the cell.

A Balancing Act: Direct and Indirect Active Transport

Chapter 8 Transporters and Active Membrane Transport Principles of Membrane Transport Chapter 8 Transporters and Active Membrane Transport Principles of.

ATP Powered Pumps By Adam Attebery.

Cell Biology Lecture 4. Plasma Membrane Transport Permeable Slightly permeable Impermeable.

Solute Transport HORT 301 – Plant Physiology September 15, 2008 Taiz and Zeiger, Chapter 6, Web Chapter 2 (p 1-10), Web Topic 6.3

Plant Mineral Nutrition: Solute Transport HORT 301 – Plant Physiology September 22, 2010 Taiz and Zeiger - Chapter 6, Appendix 1

Bacterial Physiology (Micr430) Lecture 3 Energy Production and Metabolite Transport (Text Chapters: 4, 16)

Chemistry: An Introduction to General, Organic, and Biological Chemistry, Twelfth Edition© 2015 Pearson Education, Inc Cell Membranes Substances.

Membrane transport: The set of transport proteins in the plasma membrane, or in the membrane of an intracellular organelle, determines exactly what solutes.

Cell Membrane. Chapter Outline 1) Plasma Membrane Structure and Function 2) Permeability of the Plasma Membrane 3) Diffusion and Osmosis 4) Transport.

Membranes and Transport Chapter Membrane Structure  Biological membranes contain both lipid and protein molecules  Fluid mosaic model explains.

The Movement of Substances Across Cell Membranes

Transport Across Membranes

Transport Through Membranes. Necessity for Transport Plasma Membranes Intracellular Membranes (Organelles)

CHAPTER 12 Membrane Structure and Function. Biological Membranes are composed of Lipid Bilayers and Proteins -Biological membranes define the external.

Membrane Protein Pumps. Learning objectives You should be able to understand & discuss: Active transport-Na + /K + ATPase ABC transporters Metabolite.

Membrane Structure & Function. Membrane Models Sandwich Model Present Fluid-Mosaic Model.

UNIT 6. BIOMEMBRANES AND TRANSPORT.  Introduction.  Lipids structures spontaneously formed in water.  Fluid Mosaic model.  Properties of the membranes.

Lecture Cell Chapters 5 and 6 Biological Membranes and

Vander’s Human Physiology The Mechanisms of Body Function Tenth Edition by Widmaier Raff Strang © The McGraw-Hill Companies, Inc. Figures and tables from.

CELL MEMBRANE: STRUCTURE. Title your notes Cell Membrane: Structure and Transport After notes are complete, re-read your notes and write a summary in.

Chapter 4 Movement of Molecules Across Cell Diffusion Mediated transport system - faciliated transport - active transoprt Osmosis Endocytosis and exosctosis.

THE CELL Membrane Notebook Page 33 & 34. Cell Membrane Also called the Plasma Membrane.

Discussion Questions – in your notes 1. Movement across a cell membrane without the input of energy is described by what term? 2. A substance moves from.

Cell Membrane & Transport  Fluid mosaic model - Lipids, proteins & carbohydrates  Membrane trafficking - Passive Transport - Active Transport - Bulk.

(c) The McGraw-Hill Companies, Inc.

Membranes. What is the relationship between the mosaic structure of the cell membrane and it’s function?  Osmosis and diffusion effects on biological.

THE CELL MEMBRANE CHAPTER 5. Fluid Mosaic Model Fundamental Architecture of Cell Membranes Phospholipid Bilayer Transmembrane Proteins Interior protein.

Permeability Of Lipid Bilayer Smaller and more hydrophobic molecules diffuse across membrane more rapidly.

Membrane Structure and Function Ch 12, Stryer Short Course.

Facilitated Diffusion and Active Transport

Cell Transport Ch. 7.3 & 7.4.

Membrane Structure and Function The plasma membrane controls what enters and leaves the cell.

Lehninger Principles of Biochemistry

Membrane Protein Pumps. Learning objectives You should be able to understand & discuss: Active transport-Na + /K + ATPase ABC transporters Metabolite.

Structure of a typical eukaryotic plasma membrane.

Chapter 4 Transport of Substances Through Cell Membranes Dr. Marko Ljubković Department of Physiology 1.

General, Organic, and Biological Chemistry Copyright © 2010 Pearson Education, Inc.1 Chapter 17 Lipids 17.8 Cell Membranes.

AH BIOLOGY: CELLS AND PROTEINS- PPT 6 MEMBRANE PROTEINS: CHANNEL AND TRANSPORT PROTEINS.

History of Fluid Mosaic Model For more on this history, see: 2/membrane.htm.

Cell Membrane. Endosymbiosis Theory Origin of eukaryotes Mitochondria from aerobic bacteria living within host cell Chloroplast evolved from cyanobacteria.

Learning Outcome 1. Represent and relate the basic processes, 2. Describe the principles and mechanisms involved, 3. Illustrate the concepts underlying.

Transport Across Membranes Solutes Cross Membranes by Simple Diffusion,Facilitated Diffusion, and Active Transport The Movement of a Solute Across a Membrane.

Membrane structure Plasma membrane: helps cells regulate and adjust to continuously changing environment The cell needs to keep its internal concentration.

Passive Transport across Plasma Membrane

Transport Across Membranes: Overcoming the Permeability Barrier

Structure and functions The cytoplasmic membrane, also called a cell membrane or plasma membrane. It lies internal to the cell wall and encloses the cytoplasm.

Cells: The Living Units Part A

Lecture #3 Date ______ Chapter 8~ Membrane Structure & Function.

Cell Membranes.

Homeostasis and Transport

Ch. 7 Transport of Ions and Small Molecules Across the Cell Membrane

Membrane transport Chemistry 256.

Transport of Ion & Small Molecules Across Cell Membranes

Plasma Membrane, Osmosis, Diffusion and Water Balance.

TEK B.4B Concept: Investigate and Identify Processes Including Transportation of Molecules 11/24/2018.

CeLL membrane and transport

Biological Membranes.

The Cell Membrane.

The Cell Membrane.

Biological function of inorganic elements

Plant Cells.. Membrane.. Nutrients traffic.. Regulation..

Active Transport Chapter 7.3.

Cell Membrane! List 3 characteristics of cell membranes.

Membranes -Composed of a phospholipid bilayer with embedded proteins

Movement Through the Cell Membrane

Presentation transcript:

Chapter 11: Biological Membranes and Transport

Membranes are much more than just phospholipid

Lipid aggregates

Biological membrane composition

Membrane integral proteins

Computer algorithms are fairly descent at predicting the TM regions within membrane integral protein sequences

Membrane integral proteins

Fluid mosaic model

Biological transport via vesicle-membrane fusion

Kinetics vs. thermodynamics of transport Ionophore = chemistry’s Trojan horse.

Diffusion = high to low concentration!

Other types of biological transport

The 2003 Nobel Prize in Chemistry “for discoveries concerning channels in cell membranes”

The potassium channel is an ingenious solution to selectively allowing for potassium, but not sodium transport

7TMs = GPCRs

Beta-barrel proteins

Three general classes of transport systems

The neurotransmitter/sodium symporter protein family Yamashita et al., Nature 437, , 2005.

Phylogenomics of the NSS protein family Livesay et al., BMC Bioinformatics 8, 397, 2007.

outward open -> occluded -> inward open This scheme is fairly common Model of glucose transport into erythrocytes by GluT

Active transport uses ATP hydrolysis to go against the concentration gradient

Oxidative phosphorylation synthesizes ATP, which is driven by the flux of H+ with the concentration gradient ATPase

The ATP-binding cassette (ABC) transporters and the bacterial periplasmic binding proteins (bPBPs) bPBP ATP-binding domains Transmembrane domains Substrate -- Extracellular Periplasm Cytosol -- bPBP