CLINICAL & TRANSLATIONAL SCIENCE AWARDS The Importance of Community Engagement J. Lloyd Michener, MD Professor and Chair Director, Duke Center for Community.

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Presentation transcript:

CLINICAL & TRANSLATIONAL SCIENCE AWARDS The Importance of Community Engagement J. Lloyd Michener, MD Professor and Chair Director, Duke Center for Community Research Department of Community and Family Medicine Duke University School of Medicine Ohio State University Department of Family Medicine January 22, 2009

Re-engineering Clinical Research BenchBedsidePractice Building Blocks and Pathways Molecular Libraries Bioinformatics Computational Biology Nanomedicine Translational Research Initiatives Integrated Research Networks Clinical Research Informatics NIH Clinical Research Associates Clinical Outcomes Interdisciplinary Research Innovator Award Public-Private Partnerships Cross-cutting: Harmonization, Training

NIH Clinical and Translational Science Awards... and Beyond  Catalyze change - break silos, break barriers, and break conventions  Advance the new intellectual discipline of clinical and translational science  Integrate resources and training  Identify and remove impediments to clinical and translational science

Clinical and Translational Science Award (U54)  Trans-NIH collaboration  First RFA released October, 2005  reviewed in summer of 2006 for October 2006 funding  U54 mechanism  Cooperative agreement between awardee academic institution and NIH  Multi-faceted research program  Complex award mechanism: Combined U54, T32 and K12  5 year award

MT WY ID WA OR NV UT CA AZ ND SD NE CO NM TX OK KS AR LA MO IA MN WI IL IN KY TN MS AL GA SC VA WV MI PA NJ MA ME VT NH AK HI UC, Davis Duke UCSF University of Rochester OHSU UT, Houston Mayo Clinic Columbia Yale OH University of Washington Emory University of Iowa University of Michigan Washington University, St. Louis Vanderbilt Weill Cornell FL Since 2007 Since 2006 University of Chicago Rockefeller University of Pennsylvania Johns Hopkins UT Southwestern Case Western Reserve NY University of Wisconsin Participating Institutions University of Pittsburgh Building a National CTSA Consortium Stanford Scripps Univ. of Utah Univ. of Colorado Harvard Boston University Tufts University OSU UNC Univ of Alabama at Birmingham Indiana University Northwestern UT San Antonio Albert Einstein Since 2008

Trial Design Advanced Degree-Granting Programs Participant & Community Involvement Regulatory Support Biostatistics Clinical Resources Biomedical Informatics Clinical Research Ethics CTSA Academic Center NIH & other government agencies Healthcare organizations Industry Key Functions

Strategic Planning Goal One: Enhancing National Clinical and Translational Research Capability  clinical research management  research infrastructure  phenotyping - human and preclinical models Goal Two: Enhancing the Training and Career Development of Clinical and Translational Scientists

Strategic Planning Goal Three: Enhancing Consortium-Wide Collaborations  National Resource Inventory  Data Sharing Network  Social Networking Initiative Goal Four: Enhancing the Health of Our Communities and the Nation  National Model for Community Engagement  Inform Public Health Policy Through Research

Consortium Governance & Organization Governance Manual available at Recent CTSA Community Engagement Activities Established 4 topic-based workgroups:  Community-Based Academic and Practice partnership Workgroup  Education Workgroup  Resource Development  Regional Workshops Workgroup  Workshop May 9, 2008 in Bethesda, MD: “Accelerating the Dissemination and Translation of Clinical Research into Practice”  May 14-15, 2009 NIH workshop: “Improving Health WITH Communities: The Role of Community Engagement in Clinical and Translational Research”  5 Regional Workshops 2008 Jointly Sponsored by NCRR and APTR/CDC:

Supplemental Projects Consultation Service  Provide consultation for each CTSA to strengthen community practice links PRIMER  Practice network research infrastructure needs among CTSAs Recent CTSA Community Engagement Activities

CTSAWeb.org

The Duke Center for Community Research (DCCR) Moving the Community from Subject to Collaborative Partner  Goal: Improve the health of the community through:  Community engagement in research  Integration of practices into research structure  Linking communities, practices, researchers  Components: 1. Community Research Liaison Center 2. Community Health Research Training Center 3. Electronic Health Record 4. Demonstration Projects Regulatory Affairs Project Leaders and the Portal Office

1. Community Research Liaison Center  The connection between Duke and local communities, practices, and organizations  A virtual library:  For researchers to learn about communities  For community groups to learn about themselves  For practices to identify opportunities for improvement  Outreach and training to assist communities with data and to connect communities with researchers Status: 23 grants funded, submitted or under development  14 community-wide health committees staffed

2. Community Health Research Training Center  Train and prepare researchers and learners to work successfully with communities Electronic training modules On-site training programs Status: required training for clinicians and researchers begun with online modules and classes (2500 trained to date) go to “Find Resources”; enter keyword: community engaged research

3. Electronic Health Record  Covers citizens of Durham County  Captures data for Durham County  Develop analytic techniques  Data capture and co-variates  Meshing advanced laboratory data with long term outcomes  Produce improvement of community health status Status: Implemented in Duke practices, data analyses underway with community partners

4. Demonstration Projects  Pilot projects to see if teams of community groups, clinicians, and researchers can improve health  $ 1 million for 1 year for planning  RFA for pilot projects released Summer Requirements:  Input, support, and commitment from community  Well-integrated design for prevention/care;  Budget that demonstrates effective use of resources;  Evaluation plan that establishes measurable markers

Project Status Projects :  Adolescent Health  Asthma  Breast Cancer  Cancer  Cardiovascular Disease  Chronic Kidney Disease  Diabetes  HIV/AIDS  Insurance for Small Businesses  Maternal/child health  Obesity (0-5)  Obesity (Latinos)  Obesity and Wellness  Organ Donation  Pain Management  Prostate Cancer  Seniors (Aging in Place)  Seniors (Fall Prevention)  Substance Abuse  Substance Abuse (Youth)  Youth Violence  Number of Proposals Received: 22  Number of Team Members: 413 Duke affiliated: 237 (57%) Durham: 176 (43%)  Number of Community Agencies, Organizations, and Businesses Represented: 90

More information:  CTSA:  Community Engagement Training Modules:  go to “Find Resources”; enter keyword: community engaged research  Durham Projects:  Michener JL, Yaggy S, Lyn M. Warburton S, Champagne M, Black MA, Cuffe M, Califf R, Gilliss C, Williams RS, Dzau VJ. Improving the Health of the Community: Duke’s Experience with Community Engagement. Acad Med. 2008; 83:  Principles of Community Engagement CDC/ATSDR Committee on Community Engagement Centers for Disease Control and Prevention Public

New Challenges Require New Solutions… …Solutions that Combine Innovation with Community Engagement