結構生物學期中報告 M93360001 洪國勝. Structure and Mechanism of the Lactose Permease of Escherichia coli Science Agust 2003 VOL 301 P610-615 Jeff Abramson, Irina.

Slides:

Advertisements

Similar presentations

The lac operon.

Advertisements

控制原理與設計期中報告指導教授：曾慶耀學號：學生：楊長諺.  Introduction  System Modeling of the PMAC Motor  Neural - Network - Based Self - Tuning PI Control System.

Lac Operon & Mutants. lac Operon lacZlacYlacAoCAPplacI β-galactosidase, 3.1 kb mRNA, 120 kD (1)glc-gal  glc + gal (2)β-1-4 lactose  β-1-4 allolactose.

1 Vol. 01. p Vol. 01. p Vol. 01. p.20.

1 Vol. 03. p Vol. 03. p Vol. 03. p.21.

1 Vol. 02. p Vol. 02. p Vol. 02. p.19.

1 Vol. 03. p Vol. 03. p Vol. 03. p.16.

1 Vol. 02. p Vol. 02. p Vol. 02. p.30.

1 Vol. 03. p Vol. 03. p Vol. 03. p.35.

1 Vol. 02. p Vol. 02. p Vol. 02. p.10.

1 Vol. 01. p Vol. 01. p Vol. 01. p.14.

Some Results on Disk Graphs 陳哲烱中國科技大學 ( 台灣 ) Joint work with 李國偉、林瑩貞.

Membrane Protein Structure and Assembly Ross Dalbey The Ohio State University Department of Chemistry.

Environment and Phenotype Upper Sixth Biology. Aims To understand The effect of the environment on the phenotype Specific examples The function of the.

Objectives Outline the regulation of protein synthesis in bacteria. (Reference should be made to the lac operon in Escherichia coli).

The lac Operon of E. Coli AMATH 882 Lecture 8, Feb. 7, 2011.

The Lac Operon. Lactose = Galactose and Glucose Cells adapt to their environment by turning on and off genes. An operon is a cluster of bacterial genes.

Prokaryotic Gene Regulation April 22, 2015 Richard D. Howells, PhD MSB E-643

The Chapter 15 Homework is due on Wednesday, February 4 th at 11:59 pm.

Regulation of gene expression References: 1.Stryer: “Biochemistry”, 5 th Ed. 2.Hames & Hooper: “Instant Notes in Biochemistry”, 2 nd Ed.

Gene Regulation. Levels of Regulation DNA rearrangement –Immune System rearranges DNA Bacteria can change DNA in chromosomes Not as common as other methods.

Introduction of bioinformatics and Biological Database 高雄醫學大學生物醫學暨環境生物學系助理教授張學偉 2006/08/08.

國家地震工程研究中心 National Center for Research on Earthquake Engineering 1 國立台灣海洋大學河海工程學系耐震設計 ( 一 ) 單自由度結構之強迫振動鍾立來.

Figure 13.9 Initiation and elongation steps of transcription.

Regulation of gene and cellular activity

研習報告與討論研習報告與討論蔡騰寬中研院生醫所林陽生老師實驗室. Interaction of TCF4 with DP103 and FHL3.

Goals: Discuss 3 examples of transcriptional regulation -Lac operon -Coordinated gene regulation -Regulation of transcription without regulation of polymerase.

Chapter 13. Regulation of gene expression References: 1.Stryer: “Biochemistry”, 5 th Ed. 2.Hames & Hooper: “Instant Notes in Biochemistry”, 2 nd Ed.

CONTROL MECHANISMS 5.5. Controlling Transcription and Translation of Genes  Housekeeping Genes: needed at all times: needed for life functions vital.

9/21/ Control of Gene Expression Dr. Ir. Giyanto, MSi Laboratorium Bakteriologi Tumbuhan Departemen Proteksi Tanaman Fakultas Pertanian Institut.

Translation mRNA exits the nucleus through the nuclear pores In the cytoplasm, it joins with the other key players to assemble a polypeptide. The other.

結構生物學期末報告系級生物科技所學生欒媄竹學號 D 研究內容 NER 是生物體中 DNA 損害的主要修補系統。而 XPA 與 RPA 在 NER 起始的步驟中是共同作用於受損的 DNA 之 3’ 端，因此研究 XPA 和 RPA 蛋白為分析對象進行分析。 NER 是生物體中.

Integrating Concepts in Biology

Gene Regulation Gene Regulation in Prokaryotes – the Jacob-Monad Model Gene Regulation in Prokaryotes – the Jacob-Monad Model certain genes are transcribed.

The lactose (lac) operon - an example for prokaryotic gene regulation.

Chapter 16 – Control of Gene Expression in Prokaryotes

Crystal structure of the YffB protein from Pseudomonas aeruginosa suggests a glutathione-dependent thiol reductase function Alexey Teplyakiv, Sadhana Pullalarevu,

5.5 Control Mechanisms There are approximately genes that exist to code for proteins in humans. – Not all proteins are required at all times. –

8 January 2015 Disambiguating Transportation Authors with Unique ORCID(r) Identifiers Paul R. Burley, Northwestern University Transportation Library and.

© 2011 Pearson Education, Inc. Lectures by Stephanie Scher Pandolfi BIOLOGICAL SCIENCE FOURTH EDITION SCOTT FREEMAN 17 Control of Gene Expression in Bacteria.

PROKARYOTE GENE REGULATION transcriptional control post-transcriptional control post-translational control REGULATION OF TRANSCRIPTION Negative Positive.

Controlling Gene Expression. Control Mechanisms Determine when to make more proteins and when to stop making more Cell has mechanisms to control transcription.

Are genes always being transcribed and translated?

Where would you find active transport? interface with the environment…. maintain cell volume control internal environment signaling….Ca ++ gradient Lecture.

結構生物學期末報告生技所蕭孟昌學號 M Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA  Science March 1998 VOL 392 P42-48.

Structure of a typical eukaryotic plasma membrane.

Ribosomes look like tiny grains of sand which are in the cell membrane and its in all cells. This is what a ribosome looks like.

Structure Prediction and Modeling of a Eukaryotic Member of the Major Facilitator Superfamily Gaurav Narale.

Bioinformatics & Structural Biology M 生技所研一劉怡萱 M 生技所研一劉怡萱.

6/28/20161 GENE REGULATION Lac Operon &Trp Operon in Bacteria Salam Pradeep.

Offsite Work Web Guidance

(Regulation of gene expression)

Lac Operon Lactose is a disaccharide used an energy source for bacteria when glucose is not available in environment Catabolism of lactose only takes place.

The lac Operon of E. Coli AMATH 882 Lecture 11, Feb. 12, 2013

Regulation of gene and cellular activity

مبررات إدخال الحاسوب في رياض الأطفال

Gene Regulation.

Controlling Gene Expression

DNA Control Mechanisms

Control Mechanisms.

21twelveinteractive.com/ twitter.com/21twelveI/ facebook.com/21twelveinteractive/ linkedin.com/company/21twelve-interactive/ pinterest.com/21twelveinteractive/

Chapter 15 Operons.

Gene Regulation certain genes are transcribed all the time – constitutive genes synthesis of some proteins is regulated and are produced only when needed.

Department of Psychological Science, Saint Vincent College

DNA Control Mechanisms

May the Force Be With You: Unfolding Lipid-Protein Interactions By Single-Molecule Force Spectroscopy William Dowhan, Heidi Vitrac, Mikhail Bogdanov

Observing a Lipid-Dependent Alteration in Single Lactose Permeases

SLIDE SHOW II E325 Mutants.

DNA Control Mechanisms

Which group do I belong to?

Presentation transcript:

結構生物學期中報告 M 洪國勝

Structure and Mechanism of the Lactose Permease of Escherichia coli Science Agust 2003 VOL 301 P Jeff Abramson, Irina Smirnova, Vladimir Kasho, Gillian Verner, H. Ronald Kaback, So lwata Department of Biological Science, Imperial College London PDB ID :1PV6 IPV7

Escherichia coli Lactose Permease (LacY) is a particularly well-studied representative of the first subset of membrane transport proteinsand a member of the oligosaccharide/proton symport subfamily of the MFS transporters. For advandage research of LacY, the author used X-ray structure of the inward-facing confomation of LacY to discuss LacY biofunction and mechanism of suger/proton symport.

cytoplasm Plasm membrane Proton H + lactose Lac Y Lac Y transform lactose with proton as “Symport”

Structure Of Lac Y 1PV6

Structure Of Lac Y+TDG 1PV7

Structure analysis 1.Suger bindsing 2.Proton interaction sites 3.Input/release mechanism