APh161 - Lecture 2: The Rate of Things Rob Phillips California Institute of Technology (Pollard and Earnshaw)

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Presentation transcript:

APh161 - Lecture 2: The Rate of Things Rob Phillips California Institute of Technology (Pollard and Earnshaw)

The Hierarchy of Time Scales

E. Coli Cell Division: The Standard Stopwatch

E. Coli Cell Division: The Bacterial Growth Curve Other ways of counting cells 0.009/min

The Eukaryotic Cell Cycle Pollard and Earnshaw Adapted from Murray and Hunt

Cell Division Movies See CD accompanying Essential Cell Biology. There are beautiful movies of cell division.

The Processes of the Central Dogma

Timing of Gene Expression: How Cells Decide What to Eat Monod thesis

Timing of Gene Expression Lucy Shapiro et al., Stanford

Putting the Stopwatch on Cell Division and Cell Motility - the place to be! These movies allow for an estimate of the rate of actin polymerization. Show movies of cell division - problem often with the movies is no timer showing how long the video lasts in real time units. The concept is to estimate the rate of microtubule polymerization.

A reminder on the cytoskeleton

Embryonic Development: Telescoping up in Time