Module 6 Making a Case. Review Linde, 2005 Moderate improvements for mild or temp depression ONLY Table of Evidence # studies/part Study types Valid?

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Presentation transcript:

Module 6 Making a Case

Review Linde, 2005 Moderate improvements for mild or temp depression ONLY Table of Evidence # studies/part Study types Valid? Lit search? Results consistent? Outcome 26/3320RCTsYes Whiskey, 2001 Moderate improvements for mild or temp depression ONLY 14/1296RCTsYesNoYes

Study Intervention Duration Study Type Sample Outcome Casper, mg/daily 6-week RCT n= 205 Mean score (HMD) 123 I decreases: 82 C 11.6 for SJW 6.0 for placebo Table of Evidence

A – Recommendation based on consistent and good quality (level 1 study quality) patient-oriented evidence SORT Study Quality Diagnosis Scenarios Therapy/Prevention Scenarios Harm/Etiology Scenarios

A – Recommendation based on consistent and good quality (level 1 study quality) patient-oriented evidence B – Recommendation based on inconsistent and limited quality (level 2 study quality) patient-oriented evidence SORT Study Quality Diagnosis Scenarios Therapy/Prevention Scenarios Harm/Etiology Scenarios

A – Recommendation based on consistent and good quality (level 1 study quality) patient-oriented evidence B – Recommendation based on inconsistent and limited quality (level 2 study quality) patient-oriented evidence C – Recommendation based on consensus, usual practice, opinion (level 3) study quality) disease-oriented evidence SORT Study Quality All Scenarios

Patient-oriented evidence measures outcomes that matter to patients: morbidity, mortality, symptom improvement, cost reduction, and quality of life. Disease-oriented evidence measures intermediate, physiologic, or surrogate end points that may or may not reflect improvements in patient outcomes (e.g., cholesterol levels, blood chemistry, physiologic function, pathologic findings). SORT

Ebell MH, et al Strength of Recommendation Taxonomy (SORT): A Patient-Centered Approach to Grading Evidence in the Medical Literature. American Family Physician 69(3): SORT

Form a clinical question (PICO, search query) Find evidence (research) Make a case Three simple steps

Module 6 Making a Case