Ken Quinn Research Applications Administrator Information Technology Roswell Park Cancer Institute Christine O’Connell Sr. Director Laboratory Research Operations Moffitt Cancer Center

 Sample Life Cycle  Request Management  Sample and Batch Management  Reagents and Consumables  QC and Storage  Laboratory Operations  Workflow and Scheduling  Billing Capture  Data Retrieval  Queries and Reporting  Dashboards

 LabVantage LIMS for 7 Shared Resources:  Research Pathology, Genomics, Data Bank and Biorepository, Cancer Prevention and Population Science, Immune Analysis, Biostatistics and Bioinformatics  LabVantage LIMS for other Institutional Resources:  Cell and Vector Catalog, Ovarian Biobank, Ovarian Cancer Registry, Health Disparities Tracking  Remaining Shared Resources - 7  Non-LIMS Shared Resources  cGMP Facility utilizes STEMSOFT  Clinical Trails Management System: OmniComm eClinical

 LabVantage LIMS for 11 Shared Resources:  Analytic Microscopy, Biorepository, Biostatistics, Cancer Informatics, Chemical Biology, Flow Cytometry, Molecular Genomics, Proteomics, SAIL, Survey Methods, Translational  LabVantage LIMS for other Institutional Resources:  Collaborative Data Services (CDS)  Investigator Labs  Non-LIMS Shared Resources:  cGMP Facility (Cell Therapies) utilizes STEMSOFT  Clinical Trails Management System: ONCORE

 Significantly underestimated the “time” and “resources” required to implement customized LIMS solutions.  Started with the 2 most complex cores (would not recommend).  Overbuilt in many cases. Would recommend a more “Out of the Box” approach.  Science is always changing requiring frequent revision of customized solutions (i.e. Genomics)  Resources - highly customized solutions require leaving people behind to support.  Automated workflow management, blessing and a curse.  RPCI- LIMS Lite – reversion back to basic requirements and out of the box functionality  MCC- “Generic Core” solution  Request Management & Invoice Generation  Added additional features/functionality as needed

 Shared Resource Utilization Reporting  Facility Billing System (FBS) used for all reporting  Billing Excel files created by LIMS system or manual, imported into FBS  Billing file clean up accuracy is critical  Biospecimen Reporting  LIMS reporting  Multiple biobanks (and ownership) makes cross-bank reporting challenging.

 Shared Resource Utilization Reporting  LabVantage  LIMS: Captures Usage  LabVantage BioBanking: Biospecimen Management  Report Generation  QlikView (Business Intelligence Tool)  CCSG Reporting (Usage)  Invoice Generation

 Facility Billing System (FBS) manages billing  LIMS exports Excel files that are loaded into FBS.  Non-LIMS Shared Resources require manual creation for FBS billing Excel files for upload.  Lessons learned:  Capture Project, PI and Grant information in LIMS for all service requests.  Much effort is spent tracking and generating billing files for non-LIMS Shared Resources.  Accuracy of billing data critical for CCSG reporting from FBS.

 LIMS captures completed services and generates billing files  Invoice generation - LIMS exports the billings files to QlikView (Business Intelligence tool).  Invoice data is imported into the Lawson Accounts Receivable Module.  Non-LIMS billing  (Cell Therapies, Translational) for services related to the support of Clinical Trials occurs through ONCORE

 Grant Information - IFIS grant system  Grant Start & End Dates  Peer/Non-Peer  Current status  Faculty Information - Internal Application  Membership Status  Program affiliation  Publications – Internal Application  Very challenging to capture accurately (manual processes)  Developing a new data capture process

 MARCENE  Moffitt developed Research Administration Database  Source system for grants, publications, faculty affairs and research staff information.  Grant Information  Grant Start & End Dates  Peer/Non-Peer  Faculty Information  Membership Status  Program Affiliation  Publications  Utilization of Shared Resources

 GeneTegra  Federated Query tool - virtual data warehouse for reporting. Connects to many databases and creates virtual data marts.  Used to link biospecimens with cancer registry, clinical and research data.  Jasper Reports  LIMS reporting  Home grown applications:  iPubs – publication database  I2 – internal web site and SharePoint for CCSG management and tracking.

 QlikView  Business Intelligence tool that sits on top of LIMS for report generation  Connects to a variety of source systems for reporting purposes (i.e. LIMS, Marcene, BioBanking, Moffitt’s data warehouse, ONCORE)  MARCENE  Moffitt developed Research Administration Database  Source system for grants, publications, faculty affairs and research staff information.  Used as one of the source system for LIMS & QlikView  TransMed  Provides a way to query the data warehouse  i.e. Biospecimens linked with Clinical Data, Cancer Registry, etc.