Copyright © 2006 by Elsevier, Inc. Lymphatic System

Copyright © 2006 by Elsevier, Inc. Determinants of Lymph Flow The degree of activity of the lymphatic pump -smooth muscle filaments in lymph vessel cause them to contract -external compression also contributes to lymphatic pumping Figure 16-11; Guyton and Hall

Copyright © 2006 by Elsevier, Inc. Determinants of Lymph Flow Interstitial fluid hydrostatic pressureLymph Flow Figure 16-9; Guyton and Hall Figure 16-10; Guyton and Hall

Copyright © 2006 by Elsevier, Inc. Factors affecting Central Venous Pressure Figure 15-9; Guyton and Hall

Copyright © 2006 by Elsevier, Inc. Venous Pressure in the Body Figure 15-10; Guyton and Hall

Copyright © 2006 by Elsevier, Inc. Venous Valves Valve Deep vein Perforating vein Superficial vein

Copyright © 2006 by Elsevier, Inc. Cardiac Output Curves

Copyright © 2006 by Elsevier, Inc. NORMAL HYPEREFFECTIVE CARDIAC OUTPUT (L/min) RIGHT ATRIAL PRESSURE (mmHg) HYPOEFFECTIVE Copyright © 2006 by Elsevier, Inc.

Plateau of CO curve determined by heart strength (contractility +  HR)  Sympathetics   plateau  Parasympathetics (HR  )   Plateau Heart hypertrophy  ’s plateau Myocardial infarction  plateau)  Plateau The Cardiac Output Curve

Copyright © 2006 by Elsevier, Inc. Point at which plateau occurs on CO curve is determined by heart strength (contractility and HR)  Sympathetics  plateau  Parasympathetics (HR  )  plateau) Heart hypertrophy  ’s plateau Myocardial infarction  plateau) The Cardiac Output Curve

Copyright © 2006 by Elsevier, Inc. Arterial Baroreceptor Reflex Blood Pressure Arterial Baroreceptors Vasomotor Center

Copyright © 2006 by Elsevier, Inc. Anatomy of the Baroreceptors Figure 18-5; Guyton and Hall

Copyright © 2006 by Elsevier, Inc. Response of the Baroreceptors to Arterial Pressure Figure 18-6; Guyton and Hall

Copyright © 2006 by Elsevier, Inc. Response of the Baroreceptors to Pressure Constrict Common Carotids Constrictors Pressure at Carotid Sinuses Arterial Pressure Figure 18-5; Guyton and Hall Figure 18-7; Guyton and Hall

Copyright © 2006 by Elsevier, Inc. Functions of the Baroreceptors Maintains relatively constant pressure despite changes in body posture. Decrease Cardiac Output Sensed By Baroreceptors SupineStanding Decrease Central Blood Volume Vasomotor Center Sympathetic Nervous Activity Decrease Arterial Pressure

Copyright © 2006 by Elsevier, Inc. Carotid and Aortic Chemoreceptors Sympathetic activity ChemoreceptorsVMC O2 CO2 pH BP Figure 18-5; Guyton and Hall