Variation in the Human Immune System Is Largely Driven by Non-Heritable Influences Petter Brodin, Vladimir Jojic, Tianxiang Gao, Sanchita Bhattacharya,

Slides:



Advertisements
Similar presentations
How T Cells Earn the Follicular Rite of Passage Carola G. Vinuesa, Jason G. Cyster Immunity Volume 35, Issue 5, Pages (November 2011) DOI: /j.immuni
Advertisements

UpSET Recruits HDAC Complexes and Restricts Chromatin Accessibility and Acetylation at Promoter Regions Hector Rincon-Arano, Jessica Halow, Jeffrey J.
The Bacterial DnaC Helicase Loader Is a DnaB Ring Breaker Ernesto Arias-Palomo, Valerie L. O’Shea, Iris V. Hood, James M. Berger Cell Volume 153, Issue.
Aurora Kinases and Protein Phosphatase 1 Mediate Chromosome Congression through Regulation of CENP-E Yumi Kim, Andrew J. Holland, Weijie Lan, Don W. Cleveland.
Waging War on Cancer with the Sword of Immunity Cell Volume 158, Issue 2, (July 2014) DOI: /j.cell Copyright © 2014 Terms and Conditions.
SOD1 Integrates Signals from Oxygen and Glucose to Repress Respiration Amit R. Reddi, Valeria C. Culotta Cell Volume 152, Issue 1, Pages (January.
Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.
The RAG Recombinase Dictates Functional Heterogeneity and Cellular Fitness in Natural Killer Cells Jenny M. Karo, David G. Schatz, Joseph C. Sun Cell Volume.
The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity Jenni Durieux, Suzanne Wolff, Andrew Dillin Cell Volume 144, Issue 1, Pages.
TWEAK Attenuates the Transition from Innate to Adaptive Immunity Heather Maecker, Eugene Varfolomeev, Frank Kischkel, David Lawrence, Heidi LeBlanc, Wyne.
Bleach Activates a Redox-Regulated Chaperone by Oxidative Protein Unfolding J. Winter, M. Ilbert, P.C.F. Graf, D. Özcelik, U. Jakob Cell Volume 135, Issue.
Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding Aleksandra Helwak, Grzegorz Kudla, Tatiana Dudnakova, David Tollervey.
What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell
Treatment of Obesity with Celastrol
Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity Michael S. Rooney, Sachet A. Shukla, Catherine J. Wu, Gad Getz,
Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni
A Long ncRNA Links Copy Number Variation to a Polycomb/Trithorax Epigenetic Switch in FSHD Muscular Dystrophy Daphne S. Cabianca, Valentina Casa, Beatrice.
Transcriptional Control of Gene Expression by MicroRNAs Basel Khraiwesh, M. Asif Arif, Gotelinde I. Seumel, Stephan Ossowski, Detlef Weigel, Ralf Reski,
Common Sense about Taste: From Mammals to Insects David A. Yarmolinsky, Charles S. Zuker, Nicholas J.P. Ryba Cell Volume 139, Issue 2, Pages (October.
Genome-wide Single-Cell Analysis of Recombination Activity and De Novo Mutation Rates in Human Sperm Jianbin Wang, H. Christina Fan, Barry Behr, Stephen.
UvrD Helicase Unwinds DNA One Base Pair at a Time by a Two-Part Power Stroke Jae Young Lee, Wei Yang Cell Volume 127, Issue 7, Pages (December.
Nucleation and Transport Organize Microtubules in Metaphase Spindles Jan Brugués, Valeria Nuzzo, Eric Mazur, Daniel J. Needleman Cell Volume 149, Issue.
Plant Stomata Function in Innate Immunity against Bacterial Invasion Maeli Melotto, William Underwood, Jessica Koczan, Kinya Nomura, Sheng Yang He Cell.
Eph-Ephrin Bidirectional Signaling in Physiology and Disease Elena B. Pasquale Cell Volume 133, Issue 1, Pages (April 2008) DOI: /j.cell
Xenobiotics Shape the Physiology and Gene Expression of the Active Human Gut Microbiome Corinne Ferrier Maurice, Henry Joseph Haiser, Peter James Turnbaugh.
Cancer Metabolism Cell Volume 148, Issue 3, (February 2012) DOI: /j.cell Copyright © 2012 Terms and Conditions Terms and Conditions.
Computational Modeling of Pancreatic Cancer Reveals Kinetics of Metastasis Suggesting Optimum Treatment Strategies Hiroshi Haeno, Mithat Gonen, Meghan.
RTEL1 Dismantles T Loops and Counteracts Telomeric G4-DNA to Maintain Telomere Integrity Jean-Baptiste Vannier, Visnja Pavicic-Kaltenbrunner, Mark I.R.
Structurally Distinct Ca2+ Signaling Domains of Sperm Flagella Orchestrate Tyrosine Phosphorylation and Motility Jean-Ju Chung, Sang-Hee Shim, Robert A.
Predicting C4 Photosynthesis Evolution: Modular, Individually Adaptive Steps on a Mount Fuji Fitness Landscape David Heckmann, Stefanie Schulze, Alisandra.
The Monarch Butterfly Genome Yields Insights into Long-Distance Migration Shuai Zhan, Christine Merlin, Jeffrey L. Boore, Steven M. Reppert Cell Volume.
Dynein Anchors Its mRNA Cargo after Apical Transport in the Drosophila Blastoderm Embryo Renald Delanoue, Ilan Davis Cell Volume 122, Issue 1, Pages
A Recently Evolved Transcriptional Network Controls Biofilm Development in Candida albicans Clarissa J. Nobile, Emily P. Fox, Jeniel E. Nett, Trevor R.
Evolution of the Cancer Stem Cell Model Antonija Kreso, John E. Dick Cell Stem Cell Volume 14, Issue 3, Pages (March 2014) DOI: /j.stem
Nuclear Receptors, RXR, and the Big Bang Ronald M. Evans, David J. Mangelsdorf Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell
Transmembrane Receptor DCC Associates with Protein Synthesis Machinery and Regulates Translation Joseph Tcherkezian, Perry A. Brittis, Franziska Thomas,
The Landscape of Microsatellite Instability in Colorectal and Endometrial Cancer Genomes Tae-Min Kim, Peter W. Laird, Peter J. Park Cell Volume 155, Issue.
Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.
The Good Fat Cell Volume 147, Issue 7, (December 2011) DOI: /j.cell Copyright © 2011 Terms and Conditions Terms and Conditions.
P120-Catenin Mediates Inflammatory Responses in the Skin Mirna Perez-Moreno, Michael A. Davis, Ellen Wong, H. Amalia Pasolli, Albert B. Reynolds, Elaine.
A DNA-Dependent Protease Involved in DNA-Protein Crosslink Repair Julian Stingele, Michael S. Schwarz, Nicolas Bloemeke, Peter G. Wolf, Stefan Jentsch.
SRC-3 Coactivator Functional Lifetime Is Regulated by a Phospho-Dependent Ubiquitin Time Clock Ray-Chang Wu, Qin Feng, David M. Lonard, Bert W. O'Malley.
Germline Energetics, Aging, and Female Infertility Jonathan L. Tilly, David A. Sinclair Cell Metabolism Volume 17, Issue 6, Pages (June 2013) DOI:
Sensory Detection of Food Rapidly Modulates Arcuate Feeding Circuits Yiming Chen, Yen-Chu Lin, Tzu-Wei Kuo, Zachary A. Knight Cell Volume 160, Issue 5,
Unweaving the Autism Spectrum
Volume 160, Issue 1, Pages (January 2015)
Volume 154, Issue 1, Pages (July 2013)
In This Issue Cell Volume 158, Issue 5, (August 2014)
FIX It in One Go: Enhanced Factor IX Gene Therapy for Hemophilia B
Stem Cell Therapies: California Dreamin'?
Cancer Genomes Evolve by Pulverizing Single Chromosomes
David A. Tuveson, John P. Neoptolemos  Cell 
In Search of Scientific Inspiration
Volume 152, Issue 1, (January 2013)
Volume 130, Issue 6, (September 2007)
When Biology Doesn’t Add Up
Volume 143, Issue 6, (December 2010)
A Prescription for Human Immunology
Making the Most from Changes in Life
Volume 38, Issue 1, Pages (January 2013)
The Plasticity of Aging: Insights from Long-Lived Mutants
Learning from the Uncontrollable
Volume 163, Issue 4, (November 2015)
Immune Cells Exploit a Neural Circuit to Enter the CNS
Volume 163, Issue 2, (October 2015)
Volume 134, Issue 6, (September 2008)
David Hubel and Torsten Wiesel
In This Issue Cell Volume 145, Issue 3, (April 2011)
Volume 148, Issue 1, (January 2012)
Targeting Protein Stability with a Small Molecule
Presentation transcript:

Variation in the Human Immune System Is Largely Driven by Non-Heritable Influences Petter Brodin, Vladimir Jojic, Tianxiang Gao, Sanchita Bhattacharya, Cesar J. Lopez Angel, David Furman, Shai Shen-Orr, Cornelia L. Dekker, Gary E. Swan, Atul J. Butte, Holden T. Maecker, Mark M. Davis Cell Volume 160, Issue 1, Pages (January 2015) DOI: /j.cell Copyright © 2015 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure 1 Cell , 37-47DOI: ( /j.cell ) Copyright © 2015 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure 2 Cell , 37-47DOI: ( /j.cell ) Copyright © 2015 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure 3 Cell , 37-47DOI: ( /j.cell ) Copyright © 2015 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure 4 Cell , 37-47DOI: ( /j.cell ) Copyright © 2015 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure 5 Cell , 37-47DOI: ( /j.cell ) Copyright © 2015 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure S1 Cell , 37-47DOI: ( /j.cell ) Copyright © 2015 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure S2 Cell , 37-47DOI: ( /j.cell ) Copyright © 2015 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure S3 Cell , 37-47DOI: ( /j.cell ) Copyright © 2015 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure S4 Cell , 37-47DOI: ( /j.cell ) Copyright © 2015 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure S5 Cell , 37-47DOI: ( /j.cell ) Copyright © 2015 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure S6 Cell , 37-47DOI: ( /j.cell ) Copyright © 2015 Elsevier Inc. Terms and Conditions Terms and Conditions

Cell , 37-47DOI: ( /j.cell ) Copyright © 2015 Elsevier Inc. Terms and Conditions Terms and Conditions