Chapter 17 (part 2) Protein Turnover and Amino Acid Catabolism.

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Presentation transcript:

Chapter 17 (part 2) Protein Turnover and Amino Acid Catabolism

Dietary Protein Turnover

Protein Turnover Rates Vary

Ubiquitin Related Protein Degradation

Protein Ubiquitination Multiple Ubiquitins can be polymerized to each other.

What determines whether a protein will become ubiquinated?

Ubiquitinated Proteins are Degraded by the 26S Proteosome

26S Proteosome

Removal of nitrogen transaminase deaminase

Mechanisms to get rid of Ammonia Urea Uric Acid

Urea Cycle

Step 1: Formation of Carbamoyl Phosphate

Step 2: Ornithine Transcarbamyolase

Step 3: Argininosuccinate Synthetase

Step 4: Argininosuccinase Cytosolic enzyme

Step 5: Arginase

Urea Cycle

Glucose-Alanine Cycle

Catabolism of Carbon Chains From Amino Acids