“Harvesting Naturally Occuring And Engineered Proteins For Use in Synthetic Systems ” :Biotransporter Based ” Devices – From Sensors to Actuators to Fuel.

Slides:

Advertisements

Similar presentations

Cell membranes and exchange of material

Advertisements

Biological Membranes.

Chapter 4 Notes Cell Physiology Biology Hamilton Science Department.

Structure and Function

Nerve and muscle signalling © Dr Bill Phillips 2002, Dept of Physiology Rm N348 Anderson Stuart Bldg.

Plant Mineral Nutrition: Solute Transport HORT 301 – Plant Physiology October 9, 2009 Taiz and Zeiger, Chapter 6, Web Chapter 2 (p 1-10), Web Topic 6.3.

Passive and Active Transport

Cells and Their Environment

Passive Transport Section 4.1.

Homeostasis and Cell Transport

CELL MEMBRANE: STRUCTURE. Title your notes Cell Membrane: Structure and Transport After notes are complete, re-read your notes and write a summary in.

Unit 3: Cells Cell Transport.

CELLULAR TRANSPORT Chapter 3, Section 2.

Cellular Transport. I. General A. Definition = molecules moving across the cell membrane B. Cell Membrane is selectively permeable (lets some things in,

Bell Work What is the difference between osmosis and diffusion? What is similar between osmosis and diffusion?

Facilitated Diffusion and Active Transport

Phospholipids are a class of lipids and are a major component of all biological membranes. They produce tiny pores which can allow simple diffusion and.

Cell Transport Ch. 7.3 & 7.4.

Active Transport Section 4.2. Movement Against a Concentration Gradient  The transport of a substance across the cell membrane against its concentration.

Part 3: Homeostasis and Cell Transport (Chapter 5)

Movement Through The Cell Membrane. How Things Move in and Out of the Cell The cell membrane is selectively permeable, allowing some substances, but not.

Movement of Materials Through The Cell Membrane For a cell to maintain its internal environment, (i.e., achieve homeostasis) it has to be selective in.

Diffusion Through Cell Boundaries Every living cell exists in a liquid environment that it needs to survive. One of the most important functions of the.

Chapter 3: Cellular Level of Organization. Introduction Smallest unit performing vital physiological functions Sex Cells Somatic Cells Homeostasis maintained.

 The CM determines what gets in and out of cells.  Some molecules pass through easily including lipids that dissolve in the lipid layer of the CM. 

Active & Passive transport Comparison Aim: How does “active” & “passive” transport through a semi-permeable membrane occur? Objectives – Students should.

Keystone Review Passive Transport 1.A – ATP is a source of energy, and facilitated diffusion does not require the input of energy. 2.B – Facilitated diffusion.

Cell transport 7.3. Key Questions 1.What is passive transport? 2.What is active transport?

THE CELL & ITS ORGANELLES So what is a Cell? A place where chemical reactions occur.

Biology Chapter 3 3B-2 Transportation Across the Membrane.

KEY CONCEPT Cells use energy to transport materials that cannot diffuse across a membrane. 3.5 Active Transport, Endocytosis, and Exocytosis.

Cellular Transport Molecules moving across the cell membrane Cell Membrane is selectively permeable (lets some things in, some things out, but not everything)

Permeability of Cell Membrane Advanced Biology. Transport Vocabulary Concentration gradient  Difference in the concentration of a substance throughout.

Active Transport IB Biology. Key Words Active transport Sodium-Potassium pump Endocytosis Exocytosis ATP Pinocytosis Phagocytosis Intracellular vesicle.

Homeostasis, Osmosis, and Diffusion. Homeostasis I. Homeostasis – biological balance between a cell or organism and its external environment. A. In multicellular.

Processes for maintaining homeostasis Osmosis, diffusion, active transport, passive transport Warm-up Questions: What is homeostasis? Which organelle is.

Physiology The science that deals with the function of different parts of the body that keeps the human alive.

Essential Standard Bio.1.2 Analyze the cell as a living system.

Essential Standard Bio.1.2 Analyze the cell as a living system.

Structure and Function

Cellular Transport.

Transport through a membrane by Diffusion

Section 4 Cellular Transport

TEK B.4B Concept: Investigate and Identify Processes Including Transportation of Molecules 11/24/2018.

3.5 Active Transport, Endocytosis, and Exocytosis

Passive Transport This is going to show how cells transport substances in and out. 1.

3.5 Active Transport, Endocytosis, and Exocytosis

3.5 Active Transport, Endocytosis, and Exocytosis

DO NOW Name the three particles in an atom and their associated charges? Where is the majority of the mass of an atom? Which particles compose this mass?

Into to Cellular Transport

3.5 Active Transport, Endocytosis, and Exocytosis

3.5 Active Transport, Endocytosis, and Exocytosis

3.5 Active Transport, Endocytosis, and Exocytosis

3.5 Active Transport, Endocytosis, and Exocytosis

Movement of particles across the cell membrane without using energy

3.5 Active Transport, Endocytosis, and Exocytosis

Movement Across Cell Membranes

Homeostasis and Transport Review

3.5 Active Transport, Endocytosis, and Exocytosis

BELLWORK What are the three organelles that only plants have?

Passive Cell Transport

Notes: Movement of Material Across the Cell Membrane Active Transport

3.5 Active Transport, Endocytosis, and Exocytosis

3.5 Active Transport, Endocytosis, and Exocytosis

Dr. Syed Abdullah Gilani

Active/Passive Transport Endocytosis/Exocystosis

The Plasma Membrane.

Movement Through the Cell Membrane

ACTIVE TRANSPORT Active transport – the transport of a substance across the cell membrane against its concentration gradient; because the movement of.

Presentation transcript:

“Harvesting Naturally Occuring And Engineered Proteins For Use in Synthetic Systems ” :Biotransporter Based ” Devices – From Sensors to Actuators to Fuel Cell Membranes :Engineering membranes and transporters: Structure and function of membranes and membrane transporters John Cuppoletti, University of Cincinnati Supported by Army Research Office MURI and DARPA John Cuppoletti Department of Physiology University of Cincinnati

John Cuppoletti Dept of Physiology Univ of Cincinnati

Pumps, Carriers and Channels Pumps use chemical energy to create gradients Carriers use gradients to transport substances. These do not have open pores. Channels have closed and open states to transport ions and water. John Cuppoletti Department of Physiology University of Cincinnati

hClC-2 model (model3_07AB_BL020001) Homology models of eukaryotic channels pH Sensor loop ClC-2 Bacterial Structure pH Sensor loop John Cuppoletti Department of Physiology University of Cincinnati

Membrane Based Anthrax Detector John Cuppoletti Department of Physiology University of Cincinnati

SOLID SUPPORTED MEMBRANES K + LIPID ION CHANNEL BASED SENSORS John Cuppoletti Department of Physiology University of Cincinnati

Actuators John Cuppoletti Department of Physiology University of Cincinnati

Proton Transport at 116 o C, I M HCl BIOLOGICAL TRANSPORTERS CAN BE VERY STABLE John Cuppoletti Department of Physiology University of Cincinnati

Summary Biological transporters can be used to prepare useful devices. Examples of successes include a membrane based anthrax detector based on protective antigen, a water transporting actuator based on sucrose transporters, high throughput screening devices based on composite membranes containing ion channels. Evidence was presented that some transporters can function at temperatures greater than 100 degrees Centigrade. Solid supported membranes and porous membranes can be formed by self assembly. It is possible to engineer both proteins and devices. Examples studied include high throughput screening, actuators, detectors and fuel cells. Biological engineering may mean something different in future years. Supported by ARO MURI, DARPA, and NIH John Cuppoletti Department of Physiology University of Cincinnati