CNS Sequence Eye and Ear Lab March 18, 2009

Eyelids: Netter pl. 76

UCSF #173; human eyelid skin palpebral conjunctiva apocrine glands of Moll tarsal glands orbicularis oculi m. tarsal plate accessory lacrimal glands levator palpebrae m. (and tendon) superior tarsal muscle eyelashes w/ sebaceous glands (of Zeis)

levator palpebrae muscle superior tarsal muscle obicularis oculi muscle tarsal plate tarsal glands

Three Tunics of the Eye

Cornea Iris Anterior chamber Posterior chamber Ciliary body and processes Hyaloid canal Optic nerve Central retinal artery & vein Retina Choroid Sclera Vitreous chamber

Arteries and Veins of Orbit Ciliary arteries Central retinal artery and vein

EYE-2

Lens Lens capsule Lens epithelium Lens fibers

Lens fiber formation at the equator region equator

Lens and lens fibers

Corneal Epithelium Descemet’s Membrane Corneal Stroma Bowman’s Membrane Corneal Endothelium (Slide EYE-2_20X) Cornea (Type I collagen)

Cornea CF lamellae

A: Anterior chamber P: Posterior chamber A P

Anterior chamber Iris Posterior chamber Trabecular meshwork Canal of Schlemm Cornea

A: Trabecular meshwork B: Canal of Schlemm A B

Ciliary body and ciliary processes Ciliary processes Ciliary body Pigmented and non-pigmented ciliary epithelial cells

Sphincter (constrictor) pupillae [smooth muscle] Dilator pupillae [myoepithelial cells]

EYE-2 Ora serrata

Sclera Choroid Bruch’s membrane Choriocapillary layer Retina Inner limiting membrane Optic nerve fibers Ganglion cell layer Inner plexiform layer Inner nuclear layer Outer plexiform layer Outer nuclear layer Outer limiting membrane Rods and cones Retinal pigment epithelium

EYE-1 Fovea centralis

Ora serrataFovea centralis

Optic papilla (disc)

Fovea centralis Optic papilla (disk)

Outer, middle and inner ear

Semicircular ducts Endolymphatic sac and duct Cochlear duct Saccule Utricle

Ear-3 Saccule ? Cochlear duct Saccule

EAR-2 Cochlea Utricle ?? Ampulla of a semicircular duct Saccule

Ampulla of a semicircular duct Utricle (or saccule) Ampullae

Crista ampullaris Macula (with cupula)(with otolithic membrane) in Semicircular canal in Saccule and utricle

EAR-2 Macula Crista ampullaris Otolithic membrane with otoconia (otoliths) Cupula

Cochlea Base Helicotrema Cochlear Nerve Modiolus Spiral ganglion

# Ear-4 Cochlear nerve

Organ of Corti in Scala Media Scala vestibuli Scala tympani Scala media ? ?

Stria vascularis Scala media (cochlear duct) Basilar membrane Vestibular membrane Tectorial m. Scala vestibuli Scala tympani

Organ of Corti Outer hair cells Inner hair cell Inner and outer pillar cells O. phalangeal cells I. phalangeal cell Inner tunnel

Perilymph and endolymph filled spaces in cochlea Blue: perilymph Yellow: endolymph

Helicotrema Osseous spiral lamina Cochlear duct Low pitch sound (longer basilar membrane) High pitch sound (shorter basilar membrane) ? ? EAR-3