Choline/NAA Spatial Variation Lars Ewell Radiation Oncology University of Arizona Medical Center 1/25/08 1.

Slides:

Advertisements

Similar presentations

The Dependence of the Apparent Diffusion Coefficient on Voxel Location and Calculation Method Lars Ewell 1, Naren Vijayakumar Meeting of the American.

Advertisements

The DWMRI/MRS Glioma Imaging Protocol Lars Ewell University of Arizona Medical Center Department of Radiation Oncology Faculty Research Meeting 6/23/08.

1 Research Update/Review LAE 5/23/08. 2 RIN/Recurrent Disease: The Problem T1 weighted contrast enhanced MRI taken 16 months after completion of radiotherapy.

Inferior Brain Lesions Monitored Using Diffusion Weighted Magnetic Resonance Imaging Lars Ewell 1, Naren Vijayakumar 2, Jeffrey J. Rodriguez 2 and Baldassarre.

Methods to Differentiate Radiation Induced Necrosis and Recurrent Disease in Gliomas Lars Ewell University of Arizona Medical Center Department of Radiation.

1 ADC Calculations Lars Ewell Radiation Oncology University of Arizona Medical Center 2/8/08 1.

Voxel Location Dependence of Brain Metabolites as Determined by Magnetic Resonance Spectroscopy L.Ewell, A. Bhullar and B. Stea—Department of Radiation.

Bimonthly Meeting on July 22, 2008 Mathematical Model for MRS Amarjeet Bhullar.

Metabolic Concentrations and Ratios of Brain Tissue Amarjeet Bhullar, Lars Ewell, Tim McDaniel and Baldassarre Stea Department of Radiation Oncology, The.

Method for Determining Apparent Diffusion Coefficient Values for Cerebral Lesions from Diffusion Weighted Magnetic Resonance Imaging Examinations T.H.

14 Identify the fibers coursing at the blue arrow.

Matrix Multiplication The Introduction. Look at the matrix sizes.

$200 $400 $600 $800 $1000 $200 $400 $600 $800 $1000 $200 $400 $600 $800 $1000 $200 $400 $600 $800 $1000 $200 $400 $600 $800 $1000 $200.

Spatial Image Enhancement

Chapter 07 – Rate, Ratio & Variation Q1

Review of a patient with confirmed pulmonary veno-occlusive disease and nonmatched perfusion defects. a) Ventilation/perfusion lung scan with multiple.

Cedar 1-2 (row 1-2) P/T values given in mol/m^3

'. \s\s I. '.. '... · \ \ \,, I.

Bilateral cavitary plaques.

Xe-CT CBF maps in a patient with Moyamoya disease.

Patient with cholesteatoma on the right and chronic otitis media without cholesteatoma on the left. Patient with cholesteatoma on the right and chronic.

' '· \ ·' ,,,,

Slice no. 5. Slice no. 5. T2-weighted coronal image (20/9.2/12) at the level of the temporal horns (33 weeks' gestation). Large arrow, cingulate sulcus;

(A) Frequency of synchronous diagnosis of primary tumour and BM according to primary tumour type (B) Frequency of patients with asymptomatic BM at first.

Choice of the study design (superiority vs non-inferiority design) for postregistration trials comparing different treatments for the same therapeutic.

Case 2. Case 2. Organized hematoma arising from antrochoanal polyp in a 12-year-old girl. A, Contrast-enhanced axial CT scan shows marked irregular nodular.

A 22-year-old man with posterior left frontal grade 2 astrocytoma.

A, Sagittal T1 MR imaging. A, Sagittal T1 MR imaging. Multiple bone lesions with T1 hyperintensity involve the cervical and thoracic spine, with a pathologic.

Cortical Motion Deafness

Molecular spectra of BTC

FLAIR scan, FA map, and fiber tracking in a 38-year-old patient with TBI who was imaged 2 weeks after the initial trauma. FLAIR scan, FA map, and fiber.

A–C, Surgical planning, case 9 (Table 1): 18-year-old boy with life-long medically intractable seizure disorder due to a perinatal hemorrhage (A). A–C,

The posterior cerebellum, a new organ at risk?

Representative DTI fractional anisotropy (FA) and color vector map images of patient 9 with a left parietal angioma. Representative DTI fractional anisotropy.

Patients’ most feared AEs reported to be intolerable when lasting more than 7 days at baseline, on study and at study completion (% patients); (A) grade.

Dose values for 45 patient scans with use of the high-quality protocol

Change in individual tolerability assessment between baseline and study completion. Change in individual tolerability assessment between baseline and study.

Orientation and Direction

RADIOBIOLOGY OF THE EYE LENS

A 66-year-old man (T4N1M0, clinical stage IVa, patient No

Observed high incidence of prostatic calculi with the potential to act as natural fiducials for prostate image guided radiotherapy A.G.M. O'Neill, S.O.

A, Posterior planar scintigraphic image from a Tc99m-MDP bone scan demonstrates asymmetric sacral uptake without a horizontal strut in the setting of SIF.

Case 10. Case 10. Organized hematoma of the maxillary sinus in a 76-year-old woman. A, Precontrast axial CT scan with bone window setting shows a large,

Hashimoto encephalitis.

A, Axial CT of a patient with bilateral DON and lack of fat prolapse through the superior ophthalmic fissure. A, Axial CT of a patient with bilateral DON.

Variations in the shape of the superior compartment of the FSDP due to variations in the marginating air cells. Variations in the shape of the superior.

Four more examples of missed additional aneurysms on DSA

A 7-day old neonate, the older sister of patient 1, also presented with neonatal encephalopathy.Axial fast spin-echo T2-weighted image (130/4200/1[TE/TR/NEX])

Contrast-enhancing lesions on CT scans (A–D) in 4 patients with AIDS-related PCNSL. Note irregularly enhancing lesions in the right parietal lobe (A),

Patient 4: 71 year-old woman with primary angiitis of the CNS

Patient 2. Patient 2. A 31-year-old man with fever, seizures, and weakness of the left upper extremity. DW images were superior to conventional MR images.

Differentiation of common pediatric brain tumors by quantitative 1H-MR spectroscopy. Differentiation of common pediatric brain tumors by quantitative 1H-MR.

A 68-year-old woman with acute back pain of 15-day duration.

Demonstration of the medial longitudinal fasciculus (asterisk) throughout the brain stem. Demonstration of the medial longitudinal fasciculus (asterisk)

A, Sagittal T1-weighted image demonstrates a mildly hypointense well-defined mass arising from the posterior aspect of the tongue abutting the inferior.

Z-score brain surface map represents areas of metabolic reduction in patients in comparison with healthy subjects (data base group). Z-score brain surface.

Z-score brain surface map represents the result of group comparison between 2 healthy subjects groups such as control group (CG) and data base group (DBG).

A, Luxol fast blue stain of the spinal cord in a patient with AIDS-associated myelopathy (not from our series) shows pathologic changes predominantly involving.

CT scans and data analysis obtained from patient 1

Axial T2-weighted image (A) demonstrates focal cortical dysplasia (arrow) centered in the left anterior temporal lobe in a right-handed patient. Axial.

The “white gray sign.” Axial high-resolution 3D inversion recovery fast-spoiled gradient-echo T1-weighted image demonstrates decreased gray-white contrast.

Maximal variation of ASPECTS sections with baseline alteration.

Patient 10. Patient 10. A 67-year-old man after radiation therapy at an outside hospital for base-of-tongue cancer. A and B, Axial contrast-enhanced CT.

A, MR image shows a right superior frontal gyrus lesion (arrow).

A left centrum semiovale lesion in a 30-year-old woman with relapsing-remitting MS; the time lapse between 3T and 7T scans was 6 months. A left centrum.

Bar graphs of ratios of diffusion characteristics between the two sides of four structures in a patient with mild traumatic brain injury, using the immediate.

Atypical imaging findings of giant ranulas

Patient 16: gestational-week fetus.

Kaplan-Meier event-free survival from ipsilateral stroke for patients with near occlusion, pooled data from the NASCET and ECST. The 3-year intention-to-treat.

Highly specific connections between the cortical lobe and thalamus.

Presentation transcript:

Choline/NAA Spatial Variation Lars Ewell Radiation Oncology University of Arizona Medical Center 1/25/08 1

Cho/NAA Spatial Variation Cho/NAA has potential for necrosis/disease discrimination Weybright et al., Neuroradiology (2004) 46: 541–549

Patient 1: Scanned 3/23/07 S26S46

Patient 1, Cho/NAA 3/23/07 Highest ratio near center of disease/radiation. Dark blue not zero, ambiguous, indeterminate spectra.

Patient 1, Cho/NAA 5/8/07 Highest ratio moved posterior relative to 3/23/07 spectra. Dark blue not zero, ambiguous, indeterminate spectra.

Patient 1: Row and Columns

Central Increase going from Inferior to Superior Slice: Columns 6, 7, 8 Peripheral Decrease going from Inferior to Superior Slice: Columns 5, 10, 11

Similar behavior for row number 12

Closer to lesion, different behavior