Myasthenia Gravis Blaine Suing November 21 st 2007

HERE WE GO !

What is Myasthenia Gravis? Myasthenia gravis is a chronic autoimmune neuromuscular disease Myasthenia gravis is a chronic autoimmune neuromuscular disease The name myasthenia gravis, which is Latin and Greek in origin, literally means "grave muscle weakness." The name myasthenia gravis, which is Latin and Greek in origin, literally means "grave muscle weakness." Myasthenia gravis is muscle weakness that increases with activity and improves after periods of rest. Myasthenia gravis is muscle weakness that increases with activity and improves after periods of rest.

Where does the disease take place? Myasthenia Gravis takes place a the neuromuscular junction. Myasthenia Gravis takes place a the neuromuscular junction.

The areas that are most affected. Myasthenia Gravis mainly effects the eye lids, eyes, and facial movement (such as chewing or talking) which are all voluntary muscles. Myasthenia Gravis mainly effects the eye lids, eyes, and facial movement (such as chewing or talking) which are all voluntary muscles. It may also affect the muscles that control breathing, neck and limb muscles. It may also affect the muscles that control breathing, neck and limb muscles.

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Who does this affect? Both men and women can have the disease. Men over the age of 60 and women under the age of 40 are more likely to have it. But in can come at any age. Both men and women can have the disease. Men over the age of 60 and women under the age of 40 are more likely to have it. But in can come at any age. Juvenile myasthenia gravis is not un common. Juvenile myasthenia gravis is not un common. Neonatal myasthenia gravis is temporary and usually only last 2-3 months. Neonatal myasthenia gravis is temporary and usually only last 2-3 months.

Women are affected more then men at ratio 3/2. Women are affected more then men at ratio 3/2. In the united states for every 100,000 people, there are 14 people with myasthenia gravis. In the united states for every 100,000 people, there are 14 people with myasthenia gravis.

Treatment The first attempt to treat MG was on June 2 nd of The first attempt to treat MG was on June 2 nd of This was an injection of physostigmine. This was an injection of physostigmine. It was performed by Dr. Mary B. Walker. It was performed by Dr. Mary B. Walker.

Treatment (today’s) There are different forms of treatment in today's world. There are different forms of treatment in today's world. Oral pills Oral pills prednisone, azathioprine, cyclosporine IV IV Gammagard, Gammar-P, Sandoglobulin Gammagard, Gammar-P, Sandoglobulin Surgery Surgery Thymectomy Thymectomy

Patient Out look Most patients with Mg can control it with medications or surgery. Most patients with Mg can control it with medications or surgery. Only in severe cases is were the patient may have repertory distress secondary to fever or infection. Only in severe cases is were the patient may have repertory distress secondary to fever or infection.

New Studies One such study is testing the use intravenous immune globlin. One such study is testing the use intravenous immune globlin. Experts are studying the use of EN101 antisense Experts are studying the use of EN101 antisense

Diagnosing Weakness in a specific area. Weakness in a specific area. Decrease strength through out the day. Decrease strength through out the day. Rejuvenated with rest. Rejuvenated with rest.

Conflicting evidence Is thymectomy really curing the disorder, or is stopping the progression? Is thymectomy really curing the disorder, or is stopping the progression?

Credits 14 Aug Aug Jan Jan National Institute of Neurological Disorders and Stroke November 19, 2007 National Institute of Neurological Disorders and Stroke November 19, 2007 National Institutes of Health November 19, 2007 National Institutes of Health November 19, September September