DuPont™ FEA-1100: Zero ODP, Low GWP, Non-Flammable Alternative for DuPont™ FEA-1100: Zero ODP, Low GWP, Non-Flammable Alternative for HCFC-141b Helen Walter-Terrinoni Nov 12, 2010

2 Desired Properties for HCFC-141b Phase-out Environmentally sustainable  Zero ODP & Low GWP Safety & Handling  Low Toxicity  Chemical stable  Non-flammable  Suitable boiling point (25C - 35C) Good insulation performance  Low vapor thermal conductivity or Lambda  Flexibility to use high level of FEA Low conversion cost  Potential drop-in to existing process & equipment  Potential drop-in to existing formulations

3 CFC-11 HCFC-141b HCFC-141b Phase-out Options HFC-245fa HFC-365mfc Pentanes Methyl Formate Methylal H2O(CO2) Mixtures HIGH ODP LOW ODP ZERO ODP Next Generation Low GWP FEA-1100 HBA-2 AFA-L1 Next Generation Low GWP Zero ODP

4 FEA-1100 – a Sustainable & Balanced Option CF 3 CH=CHCF 3  Nonflammable (ASTM E 681 at 60 o C & 100 o C)  b.p = 33 o C  λ= o C  MW = 164 FEA-1100 (HFO-1336mzz)  ODP = 0  GWP 100 yr ITH = 9.4 (NOAA)  ATM lifetime = 24 days (NOAA)

5 FEA-1100 Challenges to Develop Low GWP FEAs Reduce GWP while maintaining other desired properties

6 Foam Expansion Agent Property Comparison

7 HCFC-141b Phase-out Option Comparisons FEA-1100 – a zero ODP & low GWP FEA with desired properties

8 Vapor pressure is very close to HCFC-141b Thermal Conductivity and Vapor Pressure Comparisons Low vapor thermal conductivity over broad temperature range Lowest thermal conductivity when temperature >150F

9 FEA-1100 vs Other Zero ODP FEAs FEA-1100 vs Other Zero ODP FEAs FEA-1100 has the best insulation performance

10 FEA-1100 Impact on FEA Mixtures Adding FEA-1100 to other zero ODP FEAs Same foam formulation & equi-molar FEAs FEA-1100 improves R- value

11 FEA-1100 Mixture – Polyester Polyol Blend FEA-1100 to 50/50 cyclopentane(c-C5)-isopentane(i-C5) mixture Same foam formulation & equi-molar FEAs FEA-1100 improves performance

12 FEA-1100 vs HCFC-141b & HFCs Superior insulation performance compared to HCFC-141b & HFCs

13 FEA Level & R-value (FEA-1100 vs HFC-245fa) * High level of HFC-245fa may cause pressure exceed drum pressure rating High level of FEA-1100 can be used without vapor pressure or flammability limitation High level of FEA-1100 can potentially improve insulation performance

14 Chemical Stability – Polyether at 50 o C for 6 months FEA-1100 is stable in a generic polyether formulation after 6 months storage at 50 o C

15 FEA-1100 is stable in a generic polyester formulation after 6 months storage at 50 o C Chemical Stability – Polyester at 50 o C for 6 months

16 FEA-1100 is soluble in commonly used polyols Polyol Solubility

17 Material Compatibility - Metal Changes after 2 weeks at 100 o C (212 o F) in FEA-1100 FEA-1100 is compatible with commonly used metals

18 Material Compatibility - Elastomers FEA-1100 is compatible with commonly used elastomers Changes after 2 weeks at room temperature in FEA-1100

19 Material Compatibility - Plastics Changes after 2 weeks at room temperature in FEA-1100 FEA-1100 is compatible with commonly used plastics

20 Toxicity Assessment 4-hr LC50: Very Low acute toxicity Skin Irritation: Non - irritating Ames Test: Non - mutagenic Chromosomal Aberration: No genetic material damage Cardiac Sensitization: Favorable cardiac sensitization potential profile 28-Day Repeat Inhalation: Favorable repeated inhalation profile FEA-1100: Favorable Results 90 Day/ developmental: Favorable repeated inhalation profile consistent with 28-day test result

21 Candidate Evaluation Customer Validation Intermediate Scale Commercial Sales Full Scale Commercial Sales Screening Candidate s Desired FEA Properties SNAP, PMN, REACH & additional tests as needed Support customer conversion Intermediate scale commercial plant Support customer testing & optimization Small lot production Manufacturability Full scale commercial plant Support customer conversion Launch FEA-1100 Supply FEA-1100 DuPont Low GWP FEA (Blowing Agent) Program ODP, GWP, Flammability, Toxicity.. Insulation performance, Stability, Solubility… Bench scale production and optimization Safety & Environmental Properties

22 FEA-1100 Summary Zero ODP & low GWP Non-flammable FEA with boiling point close to HCFC-141b [1] Proceedings of 12 th International Conference: Blowing agents and foaming processes, Cologne, Germany (2010), page 5 [2] Proceedings of Polyurethans 2010 Technicla Conference 2010, Houston, USA (2010) Good chemical and thermal stability [2] Heat of evaporation close to HCFC-141b, HFC- 245fa & cyclopentane [2] Superior insulation performance compared to HCFC-141b, HFCs (245fa & 365mfc) & pentanes (cyclopentane & Isopentane) [1] Good material compatibility and polyol solubility [1] Potential drop-in replacement with improved performance

23 Disclaimer: The information set forth herein is furnished free of charge and based on technical data that DuPont believes to be reliable. It is intended for use by persons having technical skill, at their own risk. Since conditions of use are outside our control, we make no warranties, expressed or implied and assume no liability in connection with any use of this information. Nothing herein is to be taken as a license to operate under, or a recommendation to infringe any patents or patent applications.

24