A Stem Cell Story: Quick Quiz Image: Dr David Becker/Wellcome Images This quiz is intended for use with the film A Stem Cell Story, available at www.eurostemcell.org/films

Image: Oliver Burston/Wellcome Images 1. What is a stem cell? A A cell that can make copies of itself AND make more specialized types of cell B A cell that helps to fight against infections C A cell that is specialized D A cell that can produce all the cell types of the body Image: Oliver Burston/Wellcome Images

2. Where can scientists obtain stem cells? A Only from an embryo B Only from tissues in the body C Only from the brain D From an embryo or tissues in the body Note: Stem cells can also be obtained from a fetus, umbilical cord blood or by using a recently developed technique to ‘reprogramme’ specialized cells in the body so that they behave like embryonic stem cells. These ‘reprogrammed’ cells are known as induced pluripotent stem cells (iPS cells). You can find out more about iPS cells on EuroStemCell.org Images (clockwise from top): Dr David Becker, Heidi Cartwright, Oliver Burston/Wellcome Images

Image: Annie Cavanagh/Wellcome Images 3. Embryonic stem cells can differentiate into which types of cell? A Only brain stem cells and specialized brain cells B All types of specialized cells C Only cells that can produce insulin D Only cells that can produce artificial skin Image: Annie Cavanagh/Wellcome Images

Image: Heidi Cartwright/Wellcome Images 4. Neural stem cells from the brain can differentiate into which types of cell? A Only specialized brain cells B Specialized brain cells and specialized skin cells C All types of specialized cells D Only specialized blood cells Image: Heidi Cartwright/Wellcome Images

Image: Anne Weston, LRI, CRUK/Wellcome Images 5. In the treatment of burns, scientists can use stem cells to help them replace… A All parts of the patient’s skin B Hair follicles and sweat glands C The outermost layer of the skin D All parts of the skin except sweat glands Image: Anne Weston, LRI, CRUK/Wellcome Images

Image: Wellcome Library, London 6. What are cells ‘fed’ when they are grown in a lab?   A Antibodies B Proteins and sugars C Salts D Other cells Image: Wellcome Library, London

Yorgos Nikas/Wellcome Images 7. A blastocyst is… A A very early stage embryo B A type of stem cell C Part of the blood system D A type of brain cell Yorgos Nikas/Wellcome Images

K. Hardy/Wellcome Images 8. When are blastocycsts created in a laboratory? A At weekends B When blood supplies are low C During fertility treatment D Whenever scientists are studying cells K. Hardy/Wellcome Images

Image: Wellcome Library, London 9. What are the roles of stem cells in our bodies? A We are not sure what roles stem cells play in the body B They produce new specialized cells to replace cells that die or get used up C They fight against infections D They perform specialized roles in the body (e.g. produce insulin, transmit signals in the nervous system, …) Image: Wellcome Library, London

Image: Wellcome Library, London 10. What are stem cell scientists investigating today? A When and how embryonic stem cells make decisions to produce more specialized cells B How stem cells work in the body C How stem cells might be used to treat disease D All of the above Image: Wellcome Library, London

Acknowledgements Images © Wellcome Images. Contact images@wellcome.ac.uk should you wish to use any of the images outside the context of this quiz. Thanks to Dr Christele Gonneau for development of the bulk of the content of the quiz. Thanks to Liberton High School, Edinburgh, UK for allowing us to trial the quiz with their students and providing helpful feedback.