Adult Immunization 2010 Hepatitis B Vaccine Segment This material is in the public domain This information is valid as of May 25, 2010
Risk Factors for Hepatitis B CDC Sentinel Sites. 2001 data.
Hepatitis B Vaccine Long-Term Efficacy Immunologic memory develops following vaccination Antibody level declines following successful vaccination Anamnestic response upon exposure (antibody level increases quickly) Chronic infection rarely documented among vaccine responders MMWR 2006;55(RR-16)
Hepatitis B Vaccine Adult Schedule Usual Minimum Dose Interval Interval Primary 1 Primary 2 --- --- 1 month 4 weeks Primary 3 4-6 months 8 weeks* *third dose must be separated from first dose by at least 16 weeks MMWR 2006;55(RR-16)
Booster doses are NOT recommended routinely for any group Hepatitis B Vaccine Booster doses are NOT recommended routinely for any group MMWR 2006;55(RR-16)
Hepatitis B Vaccine Adult Candidates Men who have sex with men Heterosexual with multiple partners Persons seeking evaluation or treatment for a sexually transmitted disease Injection drug users Male prison inmates Persons with end-stage renal disease, including predialysis, hemodialysis, peritoneal dialysis, and home dialysis MMWR 2006;55(RR-16)
Hepatitis B Vaccine Adult Candidates Staff and clients in institutions for the developmentally disabled Persons with chronic liver disease Persons with HIV infection Household members and sex partners of persons with chronic HBV infection Persons who travel to HBV-endemic areas MMWR 2006;55(RR-16)
Hepatitis B Vaccine Contraindications and Precautions Severe allergic reaction to a vaccine component or following a prior dose Moderate or severe acute illness MMWR 2006;55(RR-16)
Hepatitis B Vaccine Adverse Reactions Pain at injection site 13%-29% Mild systemic complaints 11%-17% (fatigue, headache) Temperature >100oF 1% Severe systemic reactions rare MMWR 2006;55(RR-16)
National Center for Immunization and Respiratory Diseases Contact Information Telephone (800) CDC-INFO Email nipinfo@cdc.gov Website http://www.cdc.gov/vaccines/ Broadcast Updates and Resources Web Page http://www.cdc.gov/vaccines/ed/webcasts.htm