Nanotechnology Cancer Research Kenneth Milne Introduction to Nanotechnology 2 December 2013 Why is it important. What are researchers trying to determine. What are the objectives.

Progression in Cancer Treatment Better Sunscreen, nanoparticles are more effective in absorbing light, especially UV light Titanium dioxide or zinc oxide nanoparticles Don’t break down in the sun Stronger protection, less exposure. Few health concerns(.01% if zinc entered blood stream) Applications to other fields: biology, chemistry, physics and egineering. In a study only .01 percent of zinc entered bloodsteam. Twice for 5 days

Nanoparticles used to detect and monitor cancer cells using nano sized imaging agents. Conjugated with biomolecular targeting ligands used to detect tumors. -Gold nanoparticles

Targeted Drug Delivery Loaded with drugs and targeted at cancer cells Able to pass through the body Infrared light, Heat up cancer cells

Future Plans -Engineer a nanoparticle that will actively interact with the immune system. -Better nanotechnologies to detect cancer and destroy it. Stop cancer before it develops. Gain approval for diagnostic tests -understand patient interactions to targeted therapies. -identify ligands that can target both tumor cells and the tumor microenvironment simultaneously Diagnose and identify cancerous cells earlier. -Use on humans and destroy tumor and cancer cells.

Works Cited Evironmental Working Group, “Nanoparticles in suncreen,” Enironmental Working Group website, March 2013, web, November 26, 2013 Acosta, Richard, “Nanotechnology in Cancer Treatment and Detection,” Paul Hansma Research Group, Hansmalab website, 18 August 2010, web/pdf, 20 November 2013 Mansoor, Ali, Mohazzabi, Pirooz, McCormick, Percival, Siavash, Jabari, “ Nanotechnolog in Cancer Prevention, Detection and Treatment: Bright Future Lies Ahead,” Inderscience Enterprises Ltd. World Review of Science, Technology and Sustainable Development, November 2007, Web, 18 November 2013 Grossman, J. H., & McNeil, S. E. (2012). “NANOTECHNOLOGY IN CANCER MEDICINE”. Physics Today, 65(8), 38-42. August 2012, Web, 26 November 2013 Jones, Dan, “Cancer Technology, Small but Heading For the Big Time,” Nature Publishing Group, Nature Website, March 2007, Web, 20 November 2013 Landau, Elizabeth, “Nanotech Cancer Treatment Shown to Work in Humans,” CNN, CNN website, 22 March 2010, 16 November 2013 Misra, R., Acharya, S., & Sahoo, S. K. (2010). “Cancer nanotechnology: application of nanotechnology in cancer therapy.” Drug Discovery Today, 15(19/20), 842-850. doi:10.1016/j.drudis.2010.08.006, 24 November 2013. Nanotechnology Now, “Current Nanotechnology Applications,” 7th Wave, Inc., Nanotechnology Now, 22 May 2012, Web, 18 November 2013 https://www.google.com/search?q=nanotechnology+imaging+agents&source=lnms&tbm=isch&sa=X&ei=eRmcUtHjEIG9yAHdfQ&ved=0CAcQ_AUoAQ&biw=1344&bih=632 http://nano.cancer.gov/objects/pdfs/CaNanoPlan.pdf http://www.dnatube.com/video/7497/Nanotechnology-and-the-future-of-cancer-treatment