PROSTATE CANCER SUPPORT GROUP - ACT REGION INC. Affiliated with the Prostate Cancer Foundation of Australia 1.

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Presentation transcript:

PROSTATE CANCER SUPPORT GROUP - ACT REGION INC. Affiliated with the Prostate Cancer Foundation of Australia 1

Who we are A friendly group of prostate cancer survivors and their partners We are NOT medical professionals but can provide information and express opinions based on our personal experiences Your GP is your first source of advice, and then an experienced, successful urologist 2

The Prostate Small gland - size of walnut Produces fluid that nourishes and protects the sperm Located beneath the bladder Surrounds the urethra in the shape of a doughnut 3

Rectum Bladder Pubic bone Prostate Urethra Testis Penis Seminal vesicle 4 4

Symptoms of prostate disease difficulty starting urination slow flow urination frequency urgent need to urinate nocturia – need to urinate during night difficulty emptying the bladder Leaking Note: sometimes there are no symptoms of disease 5

Main prostate disease conditions - 1 Benign Prostatic Hyperplasia (BPH) or Benign Prostate Enlargement (BPE): non-cancerous condition enlarged prostate difficulties with: starting, flow, frequency, urgency, nocturia, etc Treatment options: lifestyle, medication, surgery (e.g. TURP – “rebore”) 6

BPH 7

Main prostate disease conditions - 2 Prostatitis: non-cancerous condition prostate infection or inflammation symptoms can include: urination difficulty, frequency, painful urination or ejaculation, flu-type symptoms (fever, chills, aches), back, pelvic or groin pain treat with medication 8

Main prostate disease conditions – 3 Prostate cancer: malignant tumor/s develops in prostate gland may spread to other parts of the body 9

Prostate cancer Statistics - 1 Most commonly diagnosed cancer for men excluding non-melanoma skin cancers About 20,000 new cases diagnosed each year Men have 1 in 8 chance of being diagnosed with prostate cancer before age 75  Note: women’s risk of breast cancer: 1 in 11 10

2 nd most common cause of cancer deaths in men (after lung cancer) About 3,300 deaths each year (more than breast cancer deaths amongst women) Early detection can save lives 11 Prostate cancer Statistics – 2

✴ 2,525 2,580 7,276 9,703 10,342 12,670 14,234 19,403 3,091 2,897 (Males and females combined ) 12

(Males and females combined ) 7,626 4,047 2,938 2,706 2,552 2,344 2,248 1,459 1,279 1,129 13

Symptoms of early prostate cancer 14

Major risk factors Gender - only men have a prostate Age First-degree relatives (father, brother, son) with prostate cancer – two-fold or greater risk Family history of multiple cases of breast or ovarian cancer Life style - diet, exercise, smoking, etc Ethnicity – e.g. Afro-Americans Some special groups – e.g. Vietnam veterans; regional and rural men 15

Reducing risk Lifestyle – exercise, diet, etc. Don’t smoke “What’s good for your heart is good for your prostate” 16

Resolving the possibility of prostate cancer First step: talk to your GP Initial tests usually:  PSA (Prostate Specific Antigen) blood test  DRE (Digital Rectal Examination) 17

Testing policies - 1 Prostate Cancer Foundation of Australia:  should be included in evaluating initial urinary symptoms  annual testing from age 40 if family history of prostate cancer  annual testing as part of general checkup from age 50 for other men  Combination of PSA and DRE usually recommended 18

Testing policies - 2 Urological Society of Aust. and NZ:  Initial PSA and DRE at age 40 for all men, then:  High risk cases tested regularly; lower risk cases tested less frequently 19

PSA test PSA test measures the level of Prostate Specific Antigen in your blood: requires small amount of blood for analysis elevated level may indicate prostate cancer or other prostate disease single test may not be reliable if single elevated result : retest rate of change over time provides more reliable information 20

PSA levels and age PSA level increases with age: level of PSA should be compared with normal level for your age high PSA for your age could be due to conditions other than prostate cancer 21

PSA levels by age group (illustrative statistics only) 22 Source: AGEAVERAGE SERUM PSA (ng/ml) UPPER LIMIT OF NORMAL SERUM PSA (ng/ml)

DRE (Digital Rectal Examination) DRE can be undertaken by your GP. Involves insertion of gloved finger into the rectum to feel prostate for any abnormality (tenderness, enlargement, hardness, growths) Image copyright 2000 by Nucleus Communications, Inc. All rights reserved

Next step in diagnosis - consult a urologist

Consult a urologist - 2 If level of PSA and/or DRE results are of concern, the usual next step would be referral to a urologist In consultation with your GP choose an experienced, successful urologist Urologist may recommend biopsy:  small samples of prostate tissue extracted from the prostate  pathologist looks for cancer cells in the samples 25

Biopsy results Biopsy is only based on a sample of cells If no cancer cells detected:  does not guarantee that there is no cancer  further monitoring through PSA and DRE and further biopsies may be appropriate 26

Gleason score Pathologist grades any prostate cancer cells found using a scale ranging from 1 to 5 “Gleason score” calculated by adding the values for the two most common grades of cells “Grade” is determined from Gleason score:  2 to 4: very slow growing  5 to 6: slightly faster growing  7: becoming more aggressive  8: aggressive 27

Depending on PSA history, DRE and biopsy results, the urologist may propose other tests to determine the progression of the cancer: Whole body bone scan (to detect spread) CT scan MRI scan PET scan 28 Other tests

Treatment options - 1 Active surveillance or watchful waiting: frequent follow-up PSA tests possibly periodic biopsies change to other treatment if changes indicate it is warranted 29

Treatment options - 2 Surgery: Open radical prostatectomy Laparoscopic radical prostatectomy Robotic laparoscopic radical prostatectomy 30

Treatment options - 3 Radiotherapy: External beam radiotherapy (EBRT) Brachytherapy:  low dose rate seed brachytherapy or  temporary high dose rate brachytherapy (followed by EBRT) 31

Treatment options - 4 Hormone therapy - androgen deprivation therapy (ADT). May be used: in conjunction with radiation therapy or after recurrence of prostate cancer for advanced prostate cancer 32

Treatment options - 5 Treatments that may have potential: Chemotherapy and immunotherapy cryotherapy (freezing) - experimental HIFU (High Intensity Focused Ultrasound) - experimental 33

Deciding on treatment - 1 Factors to be taken into account: risk factors (family history, etc) age and life expectancy overall health “grade” (Gleason score) “stage”:  localised (T1 or T2)  locally advanced (T3 or T4)  advanced or metastatic (N+ or M+) 34

Deciding on treatment - 2 Become informed: publications and audiovisual material (e.g. see stuff on our web site) talk to other cancer survivors:  discuss with one of our members on a confidential basis  come to a monthly meeting 35

If possible, get more than one opinion on treatment options Evaluate risks and benefits of treatment Vs active surveillance Evaluate side effects for each treatment option Life expectancy considerations Discuss with partner and family Deciding on treatment

Possible side effects of treatment - 1 Surgery: urinary incontinence (often only short term and treatable), erectile dysfunction (can be long term and harder to treat) Radiotherapy: irritation of urinary tract and/or bowel, other urinary problems, erectile dysfunction, nausea, skin reactions, lethargy Hormone therapy: loss of libido, lethargy, energy loss, hot flushes, mood swings, weight gain, bone strength loss 37

Possible side effects of treatment - 2 Side effects and recovery can vary from patient to patient depending on: Skills of specialists involved Grade and Stage of the cancer Training before and after treatment (e.g pelvic floor exercises) Rehabilitation effort Age Health Lifestyle (e.g. diet, exercise) Attitude 38

The good news Usually, prostate cancer is slow growing and after treatment, survival rates are high and improving. If the cancer is localised to the prostate gland, then chances of enduring remission with minimal or manageable side effects are very good. If the cancer has advanced beyond the prostate gland its progress can usually be managed, enabling an enjoyable and useful life for many years. 39

Moral of the story - 1 Prostate cancer is the most common male cancer in Australia excluding non-melanoma skin cancers Prostate cancer can develop without any noticeable symptoms Early detection is of critical importance and facilitates effective treatment options 40

Early Detection “I’d have been here sooner if it hadn’t been for early detection” 41

Moral of the story - 2 Talk to your GP and implement a suitable PSA and DRE testing regime from age 40 If PSA or DRE or biopsy are of concern, get informed so that you can make a good decision about what treatment or management option is best for you. Ensure that you are being advised by experienced and successful specialist/s 42

Moral of the story - 3 PRIOR to agreeing to a treatment strategy:  inform yourself - see: prostate-cancer-support-act.net and  talk to members of our support group  Attend sessions run by ACT Health’s continence nurses (pre- and post-treatment)  discuss with partner and family Maintain a positive attitude - there can be a satisfactory outcome in the longer term 43

Prostate Cancer Support Group - ACT Region Inc. Phone: contact President or Secretary – details on web site Monthly electronic newsletter The Walnut – free – details on web site Our web site: prostate-cancer-support-act.net Affiliated with Prostate cancer Foundation of Australia 44

Prostate Cancer Foundation of Australia (PCFA) Helping men and their families through national network of prostate cancer support groups Funding research into prostate cancer Fostering consumer participation in cancer research Raising awareness about prostate cancer Web site: Free-call help line: