State-of-the-art Vision Correction STAAR Visian ICL State-of-the-art Vision Correction June, 2015 Kyiv

S. T. A. A. R. Surgical Surgical Technology And Advanced Research

STAAR Surgical worldwide ICL MFG Intl HQ Switzerland Fastest growing markets: Asia HQ USA

The ICL - History 1991 First implantations (Fyodorov, Russia) 1993 First modern STAAR ICL implanted (Pesando, Italy) V1-V3 1997 CE marking and official launch 1998 Latest design V4 2002 CE Marking Toric 2005 US FDA Approval 2010 Approval in Japan 2011 CE marking V4C 2013 >400k lenses implanted worldwide ! 2014 CE marking China

Proven Safety Record >500k lenses implanted globally >100k Visian Toric ICLs implanted globally Visian ICL V4C approved in every major refractive market (EU, China, Korea, Japan, Brazil, India) The Visian ICL has a track record of stable, consistently excellent clinical outcomes. Currently sold in more than 90 countries

Visian ICL® Details Posterior Chamber location Sulcus Location Safe distance from the endothelium Cosmetically invisible for patient Gain in retinal image size, increased magnification for patient Greater effective Optical Zone at the corneal plane Sulcus Location Stable location allowing for Toric design Easily removable /exchangable No fixation to surrounding tissues Does not alter shape/remove tissue maintaining treatment flexibility for the future Does not induce dry eye.

What is the ICL ? The ICL can correct: Nearsightedness (Myopia) Farsightedness (Hyperopia) Astigmatism One of the widest treatment ranges of any refractive product: From -0.5D to -18.0D Spherical correction From +0.5D to +10.0D Spherical Correction From 0.5D to 6.0D of Astigmatism correction

Visian ICL® Product Details Made of Collamer®: Collagen and HEMA copolymer Excellent biocompatibility resulting in quiet eyes Excellent transmittance and low reflectance patterns (no haloes or glare) UV chromophore which may help protect the retina from UV rays Very flexible (foldable, small incision, easy to inject, remove)

Happy Eyes after surgery Why COLLAMER? Soft and foldable and inserted through micro-incision Quicker visual recovery Because of the biocompatibility, the ICL is not recognized as a foreign body Happy Eyes after surgery Collamer contains a UV filter which protects against the negative effect of the sun on the crystalline lens and the retina. Protection of crystalline lens and retina

ICL is Very Thin < 100 um < 50 microns 500-600 um

Visian ICL with CentraFLOW Made of proprietary biocompatible Collamer material Central Optic port of 360µ, eliminates the need for PI’s Also has Extended alignment markings on the Toric model >100.000 implants

Advantages of ICL The central cornea remains entirely untouched Dry eyes complications do not occur Super Optical clarity of a lens-based additive surgery, rather than a tissue procedure My patient will have a “HD Vision” outcome without as much of the glare and halos often seen with LVC

Advantages of ICL Should my patient not like their vision, the ICL can be removed Subsequent IOL calculations for cataract surgery (when the patient is older) will not be affected since there has been no corneal refractive procedure Visual recovery is rapid

Growing indications Moderate to high myopia Patients with high expectations (HD-Vision, need for better night vision) Patients with thin corneas Patients with irregular corneas (Stable KC) Patients with large pupils

Contraindications Glaucoma Cataract, early or advanced ACD less than 2.8mm Age over 45 Non-stable KC

Benefits of ICL Wide range of correction (safe and effective also for very high degrees!) Superior quality of vision Better predictability (no healing!) and stability (no regression!) Better night vision Faster recovery No tissue is permanently removed from the cornea Removable (reversibility of the surgery) Eye remains unchanged for future procedures! Factors speaking for ICL

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