(C) 2010 Copyright - Loyola University Chicago Stritch School of Medicine, All Rights Reserved© Copyright 2015– Loyola University Chicago Stritch School of Medicine – All Rights Reserved Rapid, Self-serve Clinical Analytics: A Web and Hadoop-based Clinical Research Database (CRDB) Ron Price Associate Vice President, Informatics & Systems Development Loyola University Chicago Health Sciences Division AAMC Learning Health System Research Award Presentation February 12, 2015 Loyola University Chicago Health Sciences Division Stritch School of Medicine (SSOM)
(C) 2010 Copyright - Loyola University Chicago Stritch School of Medicine, All Rights Reserved© Copyright 2015– Loyola University Chicago Stritch School of Medicine – All Rights Reserved Awardees/Speakers: Ron Price Associate Vice President, Informatics and Systems Development Loyola University Chicago Health Sciences Division * LUHS CTO & CISO Richard Kennedy, PhD Vice Provost for Research and Graduate Programs Loyola University Chicago Health Sciences Division
(C) 2010 Copyright - Loyola University Chicago Stritch School of Medicine, All Rights Reserved© Copyright 2015– Loyola University Chicago Stritch School of Medicine – All Rights Reserved CRDB – Project Goals A self-service clinical research database platform 85% of preparatory-for-research projects Accessible by faculty, students, residents and staff Useable with little or no training Advanced clinical analytics platform Rapid aggregation of structured and unstructured data Allow for natural language/text processing Integrate with existing online IRB process Inexpensive and scalable
(C) 2010 Copyright - Loyola University Chicago Stritch School of Medicine, All Rights Reserved© Copyright 2015– Loyola University Chicago Stritch School of Medicine – All Rights Reserved HSD Analysts Resources and Volumes One dedicated FTE for clinical research data extracts Additional 0.5 FTE support as available Faculty, residents, students and business units as clinical data customers Preparatory-to-research requests (10-15+/week) IRB approved requests ( /year) Effort for requests varies from 1hour to several weeks
(C) 2010 Copyright - Loyola University Chicago Stritch School of Medicine, All Rights Reserved© Copyright 2015– Loyola University Chicago Stritch School of Medicine – All Rights Reserved CRDB Version 1.1 (August 2014) Current data (from Epic and IDX: /30/2014) – –Demographics – –Encounters (IP, OP, ED, OBS and Home Health) – –Procedures and clinical lab values – –Flow sheet measures (vitals, physical findings, etc.) – –Medications – –Orders – –Payor information at encounter level Widely available on the portal
(C) 2010 Copyright - Loyola University Chicago Stritch School of Medicine, All Rights Reserved © Copyright 2015 – Loyola University of Chicago Health Science Division – All Rights Reserved
(C) 2010 Copyright - Loyola University Chicago Stritch School of Medicine, All Rights Reserved © Copyright 2015 – Loyola University of Chicago Health Science Division – All Rights Reserved
(C) 2010 Copyright - Loyola University Chicago Stritch School of Medicine, All Rights Reserved © Copyright 2015 – Loyola University of Chicago Health Science Division – All Rights Reserved
(C) 2010 Copyright - Loyola University Chicago Stritch School of Medicine, All Rights Reserved © Copyright 2015 – Loyola University of Chicago Health Science Division – All Rights Reserved
(C) 2010 Copyright - Loyola University Chicago Stritch School of Medicine, All Rights Reserved © Copyright 2015 – Loyola University of Chicago Health Science Division – All Rights Reserved
(C) 2010 Copyright - Loyola University Chicago Stritch School of Medicine, All Rights Reserved © Copyright 2015 – Loyola University of Chicago Health Science Division – All Rights Reserved
(C) 2010 Copyright - Loyola University Chicago Stritch School of Medicine, All Rights Reserved © Copyright 2015 – Loyola University of Chicago Health Science Division – All Rights Reserved
(C) 2010 Copyright - Loyola University Chicago Stritch School of Medicine, All Rights Reserved © Copyright 2015 – Loyola University of Chicago Health Science Division – All Rights Reserved
(C) 2010 Copyright - Loyola University Chicago Stritch School of Medicine, All Rights Reserved © Copyright 2015 – Loyola University of Chicago Health Science Division – All Rights Reserved
(C) 2010 Copyright - Loyola University Chicago Stritch School of Medicine, All Rights Reserved © Copyright 2015 – Loyola University of Chicago Health Science Division – All Rights Reserved
(C) 2010 Copyright - Loyola University Chicago Stritch School of Medicine, All Rights Reserved© Copyright 2015– Loyola University Chicago Stritch School of Medicine – All Rights Reserved Current Stats (July 2013 – Jan 2015) Unique CRDB Users – 954 Query Tool CRDB Cohort identifications – 1,156 Defined Disease Groupings – 69 Longitudinal Chronic Diseases - 34 Analysis Modules - 31 Notable Large-Scale CRDB data extracts – –5 extracts for a recent PCORI CDRN grant – 150+K patients – –3 extracts for Chicago Health Atlas project – –FES/OSA project 24 cohorts
© Copyright 2014 – Loyola University Chicago Stritch School of Medicine – All Rights Reserved Other Planned CRDB Activities Trinity CRDB implementation 18 month build out 15.2 M patients IBM Watson analytics – CRDB as a Watson knowledge provider Fully de-identified CRDB Broaden access to other institutions Develop informatics training environment Large-scale analytics / Machine Learning
(C) 2010 Copyright - Loyola University Chicago Stritch School of Medicine, All Rights Reserved© Copyright 2015– Loyola University Chicago Stritch School of Medicine – All Rights Reserved Questions and Answers